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Mayo Clinic Research Team & Authors | Gastroenterology, Cardiology & More

February 11, 2026 Dr. Michael Lee – Health Editor Health

A collaborative research effort involving physicians and scientists at the Mayo Clinic in Rochester, Minnesota, is focused on advancing the understanding and treatment of complex liver diseases. The team, comprised of specialists from Gastroenterology and Hepatology, Family Medicine, and Cardiovascular Medicine, along with experts in Clinical Trials and Biostatistics, is investigating a range of conditions including cirrhosis, alcohol-associated hepatitis, and vascular liver disorders.

Douglas A. Simonetto, M.D., a physician specializing in gastroenterology and hepatology with subspecialty certification in transplant hepatology, is a key investigator within the Division of Gastroenterology and Hepatology. His research, as detailed by the Mayo Clinic, centers on developing new tools and therapies for preventing and managing complications arising from cirrhosis and alcohol-associated hepatitis. He is joined by Alberto Calleri, Puru Rattan, Amy Olofson, Alina Allen, Joseph C. Ahn, Patrick S. Kamath, and Vijay H. Shah in this division.

The research extends beyond the traditional boundaries of liver disease, incorporating perspectives from other medical disciplines. David Rushlow, Matthew E. Bernard, Gagandeep Singh, Mark E. Deyo-Svendsen, Graham King, and Stephen K. Stacey from the Department of Family Medicine are contributing to the collaborative effort. Kan Liu, Paul A. Friedman, Zachi I. Attia, and Peter A. Noseworthy from the Department of Cardiovascular Medicine are too involved, suggesting a focus on the interplay between liver health and cardiovascular function.

Supporting the clinical research are Blake A. Kassmeyer and Ryan J. Lennon from the Division of Clinical Trials and Biostatistics, highlighting the importance of rigorous data analysis in evaluating the effectiveness of new treatments and interventions. Dr. Simonetto received his medical degree from Health Sciences Federal University of Porto Alegre, according to US News &amp. World Report.

Dr. Simonetto’s clinical expertise encompasses a broad spectrum of liver-related conditions, including vascular liver disorders, alcohol-associated liver disease and alcohol-associated hepatitis, ascites and hepatorenal syndrome, Fontan-associated liver disease, telomere biology disorders, and acute-on-chronic liver failure. He is affiliated with Mayo Clinic Hospital Methodist Campus and Mayo Clinic Hospital Saint Marys Campus, and welcomes new patients, according to WebMD.

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