Author Correction Published: Structural Details of Light-Driven proton Pump heliorhodopsin Confirmed
A correction to a recently published study clarifies and confirms the crystal structure of heliorhodopsin, a light-sensitive protein crucial to understanding microbial life and potential bio-inspired technologies. The updated findings, published by an international team of researchers, refine the understanding of this proton pumpS mechanism and offer a more precise blueprint for future investigations.
Heliorhodopsin, discovered in 2017 in the haloarchaeon Halorubrum lacusprofundi, functions as a light-driven proton pump, converting light energy into an electrochemical gradient. This process is essential to energy production in many microorganisms and has sparked interest in its potential applications in areas like solar energy conversion and optogenetics. The initial structural determination faced challenges due to the protein’s inherent flexibility and the difficulty in obtaining high-quality crystals. This author correction addresses those challenges, providing a more robust and accurate structural model.
The research team included Yoshizumi, Kota Katayama, Satoshi P. Tsunoda, and Hideki kandori from the Department of Physics, nagoya University and OptoBioTechnology Research Center, Nagoya Institute of Technology. Additional contributors where Keiichi Inoue (The Institute for Solid State Physics, The University of Tokyo, PRESTO, Japan Science and Technology Agency), Yuji Furutani (Department of Life and Coordination-Complex Molecular Science, Institute for Molecular Science, National Institutes of Natural Sciences, and Department of Structural Molecular Science, The Graduate University for Advanced Studies (SOKENDAI)), Keitaro Yamashita (RIKEN SPring-8 Center), Kento Ikeda (School of Mathematical and Physical Sciences, Graduate School of Natural Science & Technology, Kanazawa University), Mikihiro Shibata (Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, and High-speed AFM for Biological Application Unit, Institute for Frontier Science Initiative, Kanazawa University), Alina Pushkarev and Oded Béjà (Faculty of Biology, Technion-Israel Institute of Technology), and Takayuki Uchihashi (Department of Physics, Nagoya University and Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences).