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BNITM Virus Collection Aids Global Research Efforts

global Virus Research Gets Boost as EVA Gains International Status

international non-profit status, enhancing global virus research and access to critical virus materials.Learn more about this vital initiative.">

The European Virus archive (EVA), a crucial resource for virus research, has been officially recognized as an international non-profit organization (AISBL) under Belgian law, marking a important step in bolstering global pandemic preparedness. This new status provides EVA with enhanced stability and visibility, ensuring researchers worldwide have reliable access to high-quality virus materials.The Bernhard Nocht Institute for tropical Medicine (BNITM) plays a key role in this initiative, contributing a ample collection of highly pathogenic tropical viruses.

EVA stands as the only research infrastructure globally dedicated solely to the collection, characterization, production, and distribution of reference viruses. Since its inception in 2008, the network has supplied rigorously tested virus strains and diagnostic materials to support research, vaccine development, and public health efforts. With the establishment of EVA AISBL,the platform now unites 20 scientific institutions from Europe,Australia,and beyond,including universities,research centers,and state health authorities.

Did You Know? The Global Virome Project estimates that there are approximately 1.67 million undiscovered viruses in mammals and birds, many of which could potentially spill over into humans. Understanding and archiving thes viruses is crucial for preventing future pandemics.

BNITM’s Vital Role in Virus Archiving

The BNITM makes a unique contribution by housing viruses from tropical regions within its high-security laboratories, which are classified as protection stages 3 and 4. The institute currently offers approximately 200 virus-related products, including:

  • Lassa virus strains from West Africa (2004-2014)
  • Various filoviruses, such as Ebola and Marburg virus
  • Crimean-Congo hemorrhagic fever virus from Afghanistan
  • Chikungunya, Dengue, and Yellow Fever viruses
  • Rare arenaviruses (e.g., Machupo, Guanarito) and hantaviruses (e.g., Dobrava-Belgrade, Tula)

Many of these viruses originate from patient samples collected during outbreaks, such as the Ebola epidemic in West Africa from 2014 to 2016 and Lassa fever outbreaks. Virus-derived products, such as purified RNA, are notably valuable for diagnostics and test development under secure conditions.

Germany’s Strong Presence in the EVA Network

Alongside the BNITM, other prominent German institutions, including the robert Koch Institute (RKI), the Friedrich Loeffler Institute (FLI), the DSMZ (German Collection of Microorganisms and Cell Cultures), and the Charité-University Medical center Berlin, are integral members of the EVA network. Together, they provide a wide range of expertise, spanning from tropical medicine to animal diseases and plant virology.

Pro Tip: Researchers can access the EVA catalog to find specific virus strains and related materials for their research. This centralized resource streamlines the process of obtaining critical resources for studying infectious diseases.

A Contribution to Global Health Security

“Our virus archives make a specific contribution to global virus research in the health sector,” states Prof. Dr. Stephan GĂĽnther, head of virology at BNITM. “Through EVA, we provide unique materials for the development of vaccines, medications, and diagnostics, benefiting regions where these pathogens are endemic.”

EVA’s Global Expansion

With its new legal structure,EVA is expanding its international reach. New partners from Switzerland, Greece, the Netherlands, and, for the first time, Australia are joining the network. The Australian research authority CSIRO brings high-security infrastructure and expertise in handling zoonotic and emerging viruses. Institutions such as the RIVM (Netherlands), the University of Basel, and the Hellenic Pasteur Institute are also now part of the alliance.

One Virology for One Health

The “One Virology” concept emphasizes virology as a connecting element between humans, animals, and the environment-a core principle of the One Health approach.EVA provides a enduring, communal infrastructure that supports research, diagnostics, and pandemic prevention worldwide.

Key Participants in the EVA Network
Institution country Expertise
Bernhard Nocht Institute for Tropical Medicine (BNITM) germany Tropical Medicine, High-Pathogen Viruses
Robert Koch Institute (RKI) Germany Public Health, Infectious Disease Control
Friedrich Loeffler Institute (FLI) Germany Animal Diseases, Veterinary Medicine
CSIRO australia Zoonotic and Emerging Viruses
RIVM Netherlands Public Health, Infectious Disease Research

What impact do you think the internationalization of EVA will have on global pandemic preparedness? How can researchers leverage the resources provided by EVA to accelerate the development of new diagnostics and treatments for viral diseases?

Evergreen Insights: The Importance of Virus Archives

Virus archives like the BNITM’s collection and the broader EVA network are critical for understanding and combating infectious diseases.These archives serve as repositories of viral strains,allowing researchers to study their characteristics,develop diagnostic tools,and create vaccines and therapies. The increasing globalization and climate change are driving the emergence and spread of novel viruses, making these resources more significant than ever. The World Health Organization (WHO) emphasizes the need for robust surveillance systems and research infrastructure to detect and respond to potential pandemics effectively.

The One Health approach, which recognizes the interconnectedness of human, animal, and environmental health, is essential for addressing viral threats. By studying viruses in different hosts and environments, researchers can gain insights into their transmission dynamics and develop strategies to prevent spillover events. International collaboration, facilitated by networks like EVA, is crucial for sharing data, expertise, and resources to tackle global health challenges.

Frequently Asked Questions About virus Research and Archives

why is it critically important to archive viruses?
Archiving viruses allows scientists to study their genetic makeup, understand how they evolve, and develop effective treatments and vaccines. These archives are crucial for preparing for future outbreaks and pandemics.
What types of viruses are stored in archives like the BNITM?
Archives typically store a wide range of viruses, including those that cause common illnesses like the flu, as well as more risky viruses like Ebola, Marburg, and Lassa fever viruses.
How do researchers access virus samples from archives?
Researchers can request access to virus samples through a formal application process,which typically involves providing details about their research project and demonstrating that they have the necessary expertise and facilities to handle the viruses safely.
What safety measures are in place when working with archived viruses?
Laboratories that work with archived viruses must adhere to strict safety protocols, including the use of personal protective equipment, specialized ventilation systems, and secure storage facilities. These measures are designed to prevent accidental exposure and ensure the safety of researchers and the public.
How does the european virus archive (EVA) contribute to global health security?
EVA provides a centralized resource for virus samples and related materials, making it easier for researchers around the world to access the tools they need to study and combat viral diseases. This collaboration is essential for improving global health security and preventing future pandemics.
what is the “One virology” concept, and how does it relate to global health?
The “One Virology” concept recognizes that viruses can move between humans, animals, and the environment, and that a comprehensive approach is needed to understand and address viral threats. This approach emphasizes collaboration between different disciplines and sectors to improve global health outcomes.

Disclaimer: This article provides information for general knowledge and awareness only. It does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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