AstraZeneca Vaccine: Effectiveness, Reactions and Symptoms

The AstraZeneca vaccine against covid-19 was developed by the pharmaceutical company of the same name together with the Oxford University. It was one of the first vaccines to be known that were being developing against covid-19. Also, this is the immunization that is will apply to people from 30 to 39 years old who will be vaccinated against SARS-CoV-2 for the first time.

Next, we will tell you about some myths and realities of the AstraZeneca vaccine against covid-19, which has been talked about and discussed about its adverse effects that can cause very, very few people, although so far there is no evidence of what it is what happens and what causes it.

Symptoms After Covid 19 Vaccine from AstraZeneca

After its administration, the AstraZeneca vaccine can cause a number of side effects. According to the UNAM Traveler’s Clinic, these effects will be divided into two: local effects and general effects.

Local effects

  • Pain on palpation at the injection site (less than 60%)
  • Injection site pain (less than 50%)
  • Headache (less than 50%)
  • Fatigue (less than 50%)

General effects

  • Muscle pain (less than 40 percent)
  • General malaise (less than 40 percent)
  • Fever and chills (less than 30 percent)
  • Joint pain (less than 20 percent)
  • Nausea (less than 20 percent)

Clots with AstraZeneca?

Pharmaceuticals AstraZeneca and Johnson & Johnson have been involved in the discontinuation of their products due to the rare and strange side effects caused by the dose of these two vaccines. The effect is so rare that it has only happened to one person out of a millionThat is, it is easier for you to win the Christmas lottery than to die of thrombocytopenia.

Before you get scared and ask to suspend the AstraZeneca vaccine in the country, you should know that the World Health Organization (WHO) has indicated that the benefits of this immunization are more than the consequences that it can cause, in fact, covid-19 is more likely to cause you a similar problem.

To understand what happens with the AstraZeneca vaccine (which is applied in our country) and that of Johnson and Johnson, we consulted an epidemiologist from the UNAM School of Medicine, who told us that this is a strange phenomenon that is happening with this vaccine.

“What is known is that there is an alteration at the level of platelets that could be that in the antibodies that are generated with the vaccine have some strange relationship with platelets in some people and the activity of platelets is altered, producing at the same time a decrease in platelets and an increase in coagulation, which is contradictory “, explained Malaquías López Cervantes , epidemiologist and professor of Public Health at the Faculty of Medicine.

Is the AstraZeneca vaccine good?

The World Health Organization (WHO) has recommended the inclusion of this vaccine in the emergency list, according to its website and has been subjected to examination by the European Medicines Agency (EMA) and met the criteria that the world organization requests to submit it to the consideration of SAGE.

The EMA has extensively evaluated the data on the quality, safety and efficacy of the vaccine and has recommended that a conditional marketing authorization be granted for persons 18 years of age and older.

According to the Ministry of Health, lhe vaccine efficacy in preventing symptomatic covid-19 was 76 percent after 15 days of receiving the second dose. For the prevention of serious illnesses and hospitalizations, proved effective 100 percent.

Additionally, the results were comparable between age groups, with a vaccine efficacy of 85 percent in adults 65 years of age or older more.

How does the AstraZeneca vaccine work?

Once the chimpanzee viral vector was applied, we removed the genetic code and added the genetic material that modifies the cell for protein S, the vaccine is ready to be inoculated, but what happens when it travels through our body.

“What it is going to do is invade our cells, it is going to present the genetic material to them and our cell is going to encode it to produce the spike protein S that is going to be expressed on the surface of the cell, after which the cells immunological tests will detect that this is not a protein in our body and we will provoke an immune response that will go against protein S “, explained Jorge Baruch Díaz, in charge of the Travel Clinic at UNAM.

What is the vaccine made of?

The vaccine is made from non-replicating vectors, that is, the vector is a vehicle to generate an immune response, but that vector does not have the ability to reproduce because the genetic code is removed.

“What vehicles are we using? We use vehicles based on adenoviruses, the adenoviruses that cause the common cold in humans or chimpanzees, for AstraZeneca we are using a vector that is an adenovirus that causes colds in chimpanzees, this is the vector”, explained Jorge Baruch Díaz, head of the Traveler’s Clinic of the UNAM Faculty of Medicine.

In addition to an adenovirus that can be human or chimpanzee, there are also a series of ingredients that make up the vaccine and which gives the characteristics of the dose to be applied.




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