Daily Steps linked to Slower Alzheimer’s Progression, New Study Finds
BOSTON, MA – A new study from the harvard Brain Aging Study reveals a compelling link between daily step count and the rate of cognitive decline in older adults, especially those with elevated levels of amyloid beta, a protein associated with Alzheimer’s disease. Researchers found that increasing daily steps may correlate with a slower accumulation of tau, another protein implicated in the disease, and afterward, slower cognitive progression.
The research, published today, offers a promising avenue for preventative strategies against Alzheimer’s, suggesting that even modest increases in physical activity could build cognitive resilience. while the study showed no notable association between step count and cognitive outcomes in individuals with low amyloid beta levels, the findings are particularly encouraging for those already exhibiting early biological signs of the disease.
“We are excited that data from the Harvard Brain Aging Study have contributed to a better understanding of the importance of physical activity in maintaining brain health,” said Dr. Reisa Sperling. She added, “These findings demonstrate that it is possible to develop cognitive resilience and resistance to tau pathology in the context of preclinical Alzheimer’s disease. This is especially encouraging in our quest to prevent Alzheimer’s disease dementia, as well as reduce dementia caused by multiple factors.”
The study utilized analytical models and tracked participants through annual follow-ups for up to fourteen years, establishing a clear correlation between daily step count and brain health indicators.Researchers now plan to investigate the specific components of exercise that yield the most significant benefits, as well as the underlying biological mechanisms connecting physical activity to tau accumulation.
Future clinical trials are anticipated to build upon these results, focusing on exercise interventions for older adults at high risk for Alzheimer’s.”We want to empower people to protect their brain and cognitive health by staying physically active,” concluded Dr. Wai-Ying Wendy Yau. “every step counts, and even small increases in daily physical activity can add up over time to create lasting changes in habits and health.”
