n6 and SeqCenter Partner to Revolutionize Microbiome Research with Full-Length 16S Sequencing
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In a notable advancement for the field of microbiome research, n6 has announced a strategic partnership with SeqCenter, coinciding with the launch of SeqCenter’s groundbreaking full-length 16S sequencing service at FEMS Micro. this collaboration harnesses the power of n6’s proprietary iconPCR™ technology, promising researchers superior data quality, enhanced reproducibility, and dramatically streamlined workflows – effectively democratizing access to cutting-edge microbiome analysis.
The Challenge of Accurate Microbiome Profiling
For years,microbiome research has been hampered by inherent limitations in sequencing technologies. Traditional methods often struggle with inaccuracies stemming from chimeric sequences (artificial DNA constructs) and amplification bias, where certain microbial species are overrepresented due to preferential amplification during the sequencing process. These issues can lead to a distorted view of the true microbial landscape within a sample, hindering accurate interpretation and possibly leading to flawed conclusions.
How iconPCR™ and SeqCenter are Changing the Game
The partnership between n6 and SeqCenter directly addresses these challenges. iconPCR™ significantly reduces the formation of chimeras and minimizes amplification bias, ensuring that sequencing results accurately reflect the composition of the microbial community. Combined with SeqCenter’s implementation of PacBio long-read sequencing, this delivers species- and even strain-level taxonomic resolution – a leap forward from the limitations of short-read methods.
“We’re incredibly excited to support SeqCenter in establishing a new gold standard for microbiome analysis,” says a spokesperson for n6. ”iconPCR’s transformative potential in next-generation sequencing is now being fully realized, and this partnership will accelerate its adoption across the research community.”
Key Benefits for Researchers
- Unparalleled Accuracy: iconPCR™ dramatically reduces chimeric sequences and amplification bias, providing a more faithful representation of the microbial community.
- High-Resolution Insights: PacBio long-read sequencing enables species- and strain-level taxonomic resolution, revealing nuanced differences within microbial populations.
- robust and Reproducible Results: Studies demonstrate that iconPCR-prepared libraries yield more high-confidence reads, detect up to 10x more unique amplicon sequence variants (ASVs), and exhibit tighter clustering in diversity analyses.
- Simplified workflow: Automated normalization and pooling minimize hands-on time and reduce the risk of manual errors. Researchers simply submit samples and receive actionable insights.
- Turnkey Solution: seqcenter manages the entire process, from sample intake to comprehensive analysis, making advanced microbiome profiling accessible to researchers of all levels of experience.
Beyond 16S: A Versatile Solution for NGS Workflows
The benefits of this collaboration extend beyond full-length 16S sequencing. iconPCR™‘s transformative capabilities can enhance the quality of any next-generation sequencing (NGS) workflow where data accuracy is critical. This includes applications in metagenomics, environmental monitoring, clinical diagnostics, and industrial biotechnology.
Meet the Experts at FEMS Micro
Researchers attending FEMS Micro are encouraged to visit SeqCenter at booth 31 to learn more about this innovative workflow and discuss how n6 and SeqCenter are redefining data quality in microbiome research. Don’t miss this possibility to explore the future of microbial analysis.
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