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Connective Tissue Disorders & Pregnancy: New Support for Heart Health

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PEARS Procedure Shows Promise for Aortopathy Patients During Pregnancy: A New Study

women with aortopathy,showing no aortic complications during pregnancy.">

A groundbreaking case series reveals that the Personalized External Aortic Root Support (PEARS) procedure may offer a safe pre-conception surgical option for women with aortopathy, a disease of the aorta, who are planning to become pregnant.The study, which followed seven women with nine triumphant pregnancies, found no aortic complications during pregnancy or postpartum, marking a significant step forward in managing high-risk pregnancies [1].

Understanding Aortopathy and Pregnancy Risks

Aortopathy encompasses various conditions affecting the aorta, the body’s largest artery. These conditions, such as Marfan syndrome (MFS) and Loeys-Dietz syndrome (LDS), can increase the risk of aortic dissection, a life-threatening condition where the layers of the aorta separate. Pregnancy further elevates this risk due to hormonal and hemodynamic changes.

Did You Know? Aortic dissection has a mortality rate of up to 2% per hour if left untreated, underscoring the importance of proactive management, especially in high-risk individuals.

The PEARS Procedure: A Proactive Approach

The PEARS procedure involves placing a custom-made mesh support around the aortic root to stabilize it and prevent further dilation. Research indicates that PEARS is a viable pre-emptive intervention in patients with genetic aortopathies and moderate aortic root dilation as it has the potential to stabilize the

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