Diet Rich in RNA May Slow Aging, New Research Suggests
Berlin – A balanced diet containing ample RNA may trigger protective mechanisms throughout the body, potentially slowing down aging processes, according to a new study published in Nature Communications this week. Researchers at the Max Planck Institute for Biology of Ageing found that nematodes fed an RNA-rich diet exhibited considerably higher fitness levels as they aged and experienced an increase in their overall health span.
The study, led by Dr. Elena Kyriakakis and professor Andreas Spang, reveals that RNA molecules in food initiate a systemic reaction within organisms, impacting not just local tissues but also distant organs like muscles. “We see the protective effects not just locally, but throughout the entire organism, for example in the muscles,” says Kyriakakis. This nutritional approach addresses a systemic protective reaction that enhances the body’s resilience.
Researchers observed that the roundworms experienced healthier aging and a longer health span with the RNA-rich diet. The findings suggest that individual food components can activate the body’s natural defense systems.”So a little stress is good,” explains Spang, highlighting the concept of hormesis – where mild stressors can trigger beneficial adaptive responses.
While the research was conducted on nematodes, the team believes the principle could apply to humans. The study provides further evidence that nutrition plays a crucial role in cellular health and that specific nutrients may stimulate cellular defense mechanisms. The research team’s findings underscore the importance of diet in determining how healthily individuals age.
the study is titled ”Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans” and was published on May 13, 2024 (DOI: 10.1038/s41467-025-63987-x).
