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Soybean Oil Obesity: New Research Reveals Mechanism

by Dr. Michael Lee โ€“ Health Editor
written by Dr. Michael Lee โ€“ Health Editor

Common Cooking Oil โ€‹Linked to Weight Gain and Metabolic Issues, New Research Shows

A recent study from the University of California, Riverside (UCR) โฃhas pinpointed a potential linkโ€Œ between the widespread consumption of soybean oil and obesity, as well as โคrelated metabolic problems like fatty liver disease. โคWhile notโค inherently harmful, the sheer quantity of soybean oil in โฃthe modern Americanโ€‹ diet appears to be exceeding the capacityโ€ of our bodies to process โขit effectively.

The research, published in November 2023, builds upon earlier UCR findings from 2015 demonstrating that soybean oil promotesโ€Œ weight gain moreโ€Œ readily than coconut oil.โค This latest examination goes deeper, identifying specific molecules created within the body after consuming soybean oil as โฃkey drivers of these effects.

The culprit isn’t the oil itself,or even its primary fatty acid,linoleic acid,but ratherโฃ what linoleic โคacid transforms into: oxylipins. โ€ŒExcessive intake of linoleic acid leads to increased oxylipin production, โขwich is associated with inflammation and fat accumulation.

Researchers โ€‹utilized genetically engineered โ€mice with reduced levels of enzymes responsible for converting linoleicโฃ acid and alpha-linolenic acid (another fatty acidโข in โ€‹soybean oil)โฃ intoโค oxylipins.These โฃaltered mice exhibited healthier livers and โฃenhanced mitochondrial function, โขdemonstrating resistance to weight gain โ€Œdespite consuming aโข high-fat โคsoybean oil diet. Crucially,the study found that oxylipin levels in the liver,not โฃthe blood,correlatedโ€ with body weight,suggesting standard blood tests may miss early metabolic changes.

The study also revealed a โฃsurprising connection toโค cholesterol.โฃ Despite soybean oil containing no cholesterol, miceโ€Œ consuming it showed higher cholesterol levels.

The findings โ€Œare particularly relevant given theโค dramatic increase in soybean oil consumption in the United states over the pastโ€ century. In 1923, soybeanโ€‹ oil accounted forโค approximately 2% of total calorie intake.โ€ Today, that number hasโ€ risen to nearly 10%. This surge coincides withโฃ aโ€Œ rise in ultra-processed foods, which frequently utilize soybean oil.

“Soybean oil โ€isn’tโ€ inherently evil,” explainsโ€‹ Professor Pritpalโข Deol of UCR. “But โ€‹the quantities in โ€Œwhich we โ€‹consume it is triggering pathways our bodiesโค didn’t evolve to handle.”

Researchers โคareโฃ now investigating the mechanisms โคby which oxylipin formation leads to weight gain and exploring โขwhether similar effects are observed with other oils high in linoleic acid, suchโค as corn, sunflower, and safflower oil. Whileโค human trialsโ€ are not currently planned, theโ€Œ UCR team hopes their research will inform future nutrition policy โ€Œand public health awareness,โ€‹ drawing a parallel to the decades-long delay between identifying the link between tobacco and cancer and implementing warning labels.

Source: UC Riverside – https://news.ucr.edu/articles/2025/11/26/study-links-americas-favorite-cooking-oil-obesity

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Health

Title: Diabetes Risk Reduced by Blood Sugar Control, Not Weight Loss

by Dr. Michael Lee โ€“ Health Editor
written by Dr. Michael Lee โ€“ Health Editor

Beyond the Scale: A New Approach to Diabetes Prevention

For years, the focus in diabetes prevention has been heavily weighted towards weight loss. Though,emerging research is shifting that paradigm,highlighting the critical role of muscle mass,body composition,adn metabolic healthโค over simply staring at the numbers on โคa scale.

Muscles are the body’s largest glucose stores, actively burning energy even at rest.Importantly, strength training activates GLUT-4, aโ€Œ glucose transporter that moves sugar into โ€‹cells independently of insulin. This means even a modest increase in muscle mass can significantly improve the body’s insulin response – a crucial factor inโค combating insulin resistance, the precursor โคto type 2 diabetes. Experts now recommend โฃa โ€‹combined approach of both strength and endurance training to directly address this resistance.

Simple โขlifestyle changes can โฃalso make a โ€difference. Targeted exercises integrated into daily routines can build โ€Œmuscle and enhance insulin sensitivity. (Download a freeโ€Œ report with โ€17 simple exercises here: https://gesundheitswissen-aktuell.de/lp/wunderuebungen/?af=KOOP_G_FM_DNV_YES_WUNDERUEBUNGEN_X-CWAHN-BGPID_667373)

Nutrition Reimagined

The emphasis is โคmoving away from calorie counting and towards what we eat. Prioritizing โ€fiber-rich foods – vegetables, legumes, and whole โ€Œgrains – slows down sugar absorption and prevents risky blood sugar spikes.โค Combining carbohydrates with proteinsโข and healthy fats further moderates digestion and glucose release.Even a short, 15-minuteโ€‹ walk after a meal can significantly lower blood sugar levels.

Debunking theโ€ Intermittent Fastingโ€ Myth

Recent research challenges the hype surrounding intermittent fasting. A study publishedโค November 4, 2025, in Science Translationalโ€ medicine by the Germanโ€ Institute for Nutritional Research (DIfE), known as the ChronoFastโ€‹ study, found that intermittent fasting without calorie reduction yields no โคmeasurable metabolic improvements.

The key takeaway? the timing of meals isn’t as important as altering bodyโ€‹ composition.reducing visceral belly fat, increasing muscle mass, and improving insulin sensitivity are the critical parameters forโฃ metabolic health.

The Future of Diabetes Prevention

These findingsโข are poised to reshape treatment guidelines. Future prevention โขprograms will likely prioritize metabolic markers – insulin sensitivity and body composition – โขasโ€Œ key indicatorsโข of success,rather than solelyโ€ focusing on weight.

For individuals at risk, this translates to:

* Prioritizing strength training over solelyโฃ pursuing weight loss.
* Focusing on the quality of nutrition โคratherโ€‹ than strict calorie counting.
* Making reduction of belly โขfat a primary โขgoal.
* Implementing regular blood sugar measurements โ€for monitoring.

This represents a significant paradigm shift. Diabetes prevention is becomingโ€‹ more personalized, enduring, and ultimately, more hopeful. By understanding and actively managing your metabolism,โ€‹ you can proactively address diabetes risk – without theโ€ frustrations frequently enough associated with restrictive dieting.

To gain โ€a deeper understanding of your metabolic health,consider reviewing your laboratory values. A โ€‹free โ€‹25-page report, “Laboratory โ€‹values self-check,” explains which blood values โ€are most important, how โขto interpret them, and โ€when toโ€ consult โขa doctor: https://info.gesundheitswissen-aktuell.de/laborwerte-selbstcheck/?af=KOOP_G_TG_DNV_YES_LABORWERTE-SELBSTCHECK_X-CWAHN-BGPID_667373

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Health

Discovery could lead to weight loss drugs with fewer side effects

by Dr. Michael Lee โ€“ Health Editor
written by Dr. Michael Lee โ€“ Health Editor

Weight Loss Breakthrough: New Approach Targets ‘Support Cells’ for Fewer Side Effects

Scientists discover a novel way to curb appetite by bypassing common gastrointestinal issues linked to popular slimming drugs.

Researchers have pinpointed a fresh strategy for weight management, aiming to mitigate the nausea and vomiting that deter many patients from continuing popular weight-loss medications. This innovative approach focuses on the brain’s “support” cells rather than neurons, potentially offering a gentler path to reduced appetite and improved glucose control.

A Shortcut to Appetite Control

Current medications like Ozempic, which target brain neurons to control appetite, often lead to significant gastrointestinal distress. It’s estimated that up to 70% of patients discontinue these treatments within a year due to side effects. However, a multidisciplinary team led by chemistry professor Robert Doyle at Syracuse University has identified an alternative pathway.

Instead of directly targeting neurons, which are often likened to a light bulb in the brain’s intricate system, this new research investigates the role of “support” cells. These cells, analogous to the wiring and filament that allow a light bulb to function, play a crucial but less-explored role in brain activity. The team’s findings suggest these support cells could offer a less problematic route for appetite regulation.

Identifying a Novel Compound

Collaborating with experts from the University of Pennsylvania and the University of Kentucky, Doyle and his colleagues discovered that a specific chemical produced by brain cells called astrocytes could be key. Their study, published in Science Translational Medicine, details how these cells naturally create a molecule known as octadecaneuropeptide (ODN).

When administered directly into the brains of rats, ODN demonstrated the ability to suppress appetite, leading to weight loss and enhanced glucose processing. Recognizing the impracticality of direct brain injections for human treatment, the researchers engineered a modified version of the molecule. This new compound, dubbed tridecaneuropeptide (TDN), is designed for administration through standard injections, similar to existing weight-loss drugs.

Promising Results in Pre-Clinical Trials

Pre-clinical tests involving obese mice and musk shrews showed that TDN effectively promoted weight loss and improved insulin sensitivity without inducing the nausea and vomiting associated with current therapies. Doyle explained the advantage: โ€œInstead of running a marathon from the very beginning like current drugs do, our targeting downstream pathways in support cells is like starting the race halfway through, reducing the unpleasant side effects many people experience.โ€

This downstream targeting approach offers a potential solution to the common side-effect profile of GLP-1 drugs. โ€œIf we could hit that downstream process directly, then potentially we wouldnโ€™t have to use GLP-1 drugs with their side effects. Or we could reduce their dose, improving the toleration of these drugs. We could trigger weight loss signals that happen later in the pathway more directly,โ€ Doyle added.

Path to Human Trials Underway

The potential of this discovery is now being pursued by a newly launched company, CoronationBio. The firm has secured licensing for intellectual property related to ODN derivatives from Syracuse University and the University of Pennsylvania, with the explicit goal of bringing this novel treatment to patients. CoronationBio is actively partnering with other entities to advance the development of TDN, with the aim of initiating human clinical trials as early as 2026 or 2027.

The development aligns with a broader trend in obesity research, where understanding the complex interplay of brain cells is opening new therapeutic avenues. For instance, research published by the National Institutes of Health in 2023 highlighted the role of gut-brain signaling in satiety, an area that also benefits from a more holistic understanding of neurological and cellular communication. (NIH, 2023).

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Health

Early Weight Gain: Taller Adults, Not Higher Obesity Risk

by Dr. Michael Lee โ€“ Health Editor
written by Dr. Michael Lee โ€“ Health Editor

Childhood undernutrition: Weight Gain from Ages 1-10 Linked to Taller Adult Height

Table of Contents

New research published in JAMA Network Open reveals that increasing weight in undernourished children between the ages of 1 and 10 can lead to significantly taller adult height, without a corresponding increase in the risk of obesity or high blood pressure later in life. This finding challenges previous assumptions about the optimal timing for nutritional interventions and offers new hope for improving long-term health outcomes in undernourished populations.

The Impact of early Childhood Weight Gain on Adult Height

A study conducted in Mali followed 1,348 participants for 21 years, starting at an average age of 1.6 years. The results indicated that weight gain between ages 1 and 10 was significantly associated with gains in adult stature for both females and males by age 21. This suggests that interventions aimed at improving nutrition during this period can positively influence a child’s potential adult height.

did You Know? Globally, an estimated 149.2 million children under 5 years of age were affected by stunting (low height-for-age) in 2020 [https://www.who.int/news-room/fact-sheets/detail/malnutrition].

Challenging Previous Recommendations on Undernutrition Interventions

Previous research had suggested that nutritional interventions after age 2 might not be as beneficial, with concerns that weight gain in childhood coudl lead to higher blood pressure and obesity in adulthood.However, this new study challenges that view, highlighting the importance of weight gain for helping children achieve their full height potential as adults.

Beverly Strassmann, a University of Michigan professor of anthropology and lead author of the study, emphasized the importance of adult height, particularly for women. Taller women are less likely to die in childbirth, making the association between childhood nutrition and adult height a critical consideration.

Key Findings from the Mali Study

The research team’s longitudinal study in central Mali provided valuable insights into the long-term effects of childhood weight gain. The study’s unique design allowed researchers to follow children from an average age of 1.6 years to 21 years, a rarity in low-income countries in Africa.

Strassmann noted, “Our study is unique in that we considered not only the risks of childhood weight gain for higher blood pressure and BMI in adulthood but also the benefits for increased adult stature.”

Benefits of Increased Adult Stature

The health benefits of being taller in a population impacted by undernutrition are considerable. As Strassmann pointed out, taller women face a reduced risk of mortality during childbirth.This underscores the importance of addressing undernutrition throughout childhood, not just in the first 1,000 days of life.

Pro Tip: Focus on nutrient-dense foods like eggs, dairy, meat, and legumes to support healthy weight gain and growth in children.

implications for Policy and Interventions

The findings suggest that policies for undernourished settings need to consider the importance of reducing undernutrition throughout childhood. Interventions should not be limited to the first 1,000 days of life, as weight gain after age 2 can still support growth in stature and lead to taller adults who are not obese or hypertensive.

This research challenges the widespread view that nutritional interventions for children should cease at age 2, emphasizing the need for continued support and monitoring to ensure optimal growth and development.

Comparative Analysis of Undernutrition Interventions

Intervention Type Age focus Primary Goal Potential Benefits Potential Risks
Early Childhood Interventions Conception to Age 2 Prevent stunting and promote optimal development Improved cognitive function, reduced risk of chronic diseases May not fully address long-term growth deficits
Later Childhood Interventions Ages 1 to 10 Promote weight gain and increase adult height Taller stature, reduced risk of childbirth mortality (for women) Minimal risk of obesity or hypertension (as per the study)

The data suggests that a combined approach, addressing undernutrition in both early and later childhood, may yield the most complete benefits.

Evergreen Insights: Understanding childhood Undernutrition

Childhood undernutrition remains a meaningful global health challenge, particularly in low- and middle-income countries. Factors contributing to undernutrition include poverty,food insecurity,inadequate access to healthcare,and poor sanitation. Addressing these underlying issues is crucial for achieving enduring improvements in child health and development.

the long-term consequences of undernutrition extend beyond physical health, impacting cognitive function, educational attainment, and economic productivity. Investing in effective interventions to combat undernutrition is essential for building healthier and more prosperous societies.

Frequently Asked Questions About Childhood Undernutrition

Why is childhood undernutrition a global concern?
Childhood undernutrition affects millions globally, hindering physical and cognitive development. Addressing it is crucial for improving long-term health outcomes and economic productivity, especially in low-income countries.
What age range is most critical for nutritional interventions to combat undernutrition?
while the first 1,000 days (from conception to age 2) are vital, recent research indicates that interventions focusing on weight gain between ages 1 and 10 can also significantly impact adult height in undernourished children.
How does weight gain in childhood affect adult height?
A study in mali found that weight gain between ages 1 and 10 was significantly associated with increased adult height in both males and females, suggesting that improved growth during this period can help children reach their full height potential.
Does weight gain in childhood increase the risk of obesity or high blood pressure in adulthood?
the study indicated that while weight gain led to taller stature, the increased risk for obesity and hypertension was negligible, challenging previous concerns about the long-term health consequences of childhood weight gain in undernourished settings.
What are the broader implications of this research on childhood undernutrition?
this research suggests that nutritional interventions should extend beyond the first 1,000 days, particularly in undernourished settings. Policies should consider the importance of reducing undernutrition throughout childhood to support growth in stature and overall health.

The information provided in this article is for general knowledge and informational purposes only, and does not constitute medical advice.It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

what are your thoughts on extending nutritional interventions beyond the first 1,000 days? How can communities better support children’s nutritional needs throughout childhood?

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The Impact of Reducing Red Meat Consumption on Health: Benefits and Risks
Health

The Impact of Reducing Red Meat Consumption on Health: Benefits and Risks

by Chief editor of world-today-news.com
written by Chief editor of world-today-news.com

TEMPO.CO, Jakarta – CHANCE Shidqia is a graduate singer X Factor Indonesia Season 1 in 2013 he admitted that he did not eat goat meat and beef (red meat). He admits that he prefers to eat chicken than red meat. What does Fatin’s habit do to her health?

Based on clevelandclinicaccording to dietitian, Julia Zumpano, growing research has shown the negative health impacts of frequent consumption Red meat, especially processed red meat. As a result, it is important for someone to avoid or reduce eating red meat because of the health benefits. Meanwhile, red meat includes beef, goat meat or lamb.

Here are some benefits of reducing or avoiding eating beef or red meat, namely:

Improving Cardiovascular Disease Health

Red meat is high in saturated fat which can cause an increase in bad cholesterol levels and increase the risk of cardiovascular disease. As a result, avoiding red meat can improve cardiovascular disease health.

Zumpano said that high cholesterol can cause more plaque buildup and atherosclerosis, resulting in hardening of the arteries. This condition causes a person to experience an increase in cardiovascular disease, such as heart disease and stroke.

Addressing Cancer Risk

The International Agency for Research on Cancer classifies red meat as a Group 2A carcinogen which is โ€œprobably carcinogenic to humans.โ€ Carcinogens are substances with the potential to cause cancer. Additionally, a study found that consuming high levels of red meat was associated with a higher risk of cancer, especially beef.

Apart from that, processed meat is also categorized as a level 1 carcinogen, which is at the same level as cigarettes. As a result, reducing red meat consumption can reduce the risk of cancer.

Save Expenses and Protect the Environment

Zumano explains that red meat costs significantly more than vegetarian proteins, such as beans, nuts and tofu. Switching from omnivorous to vegetarian meals every week can result in significant cost savings.

Not only that, caring for livestock that produce red meat can have a significant impact on the environment. The reason, according to Zumpano, is that livestock can produce large amounts of greenhouse gases. That way, eating less red meat can help keep the earth healthy for future generations.

Overcoming Type 2 Diabetes

According to Healthlinesome studies show that red meat consumption may increase the risk of developing type 2 diabetes. One study found that replacing one serving of beef per day with one egg can lower the risk of developing type 2 diabetes. Other studies also show that swapping beef for another protein source makes the risk of developing type 2 diabetes lower.

Manage Your Weight Well

An analysis of 12 high-quality studies found that someone on a vegetarian diet for 18 weeks lost more weight than someone on a non-vegetarian diet. In addition, someone who eats a plant-based diet consumes relatively few calories and fat. Thus, someone who avoids or reduces beef consumption can manage body weight well and overcome obesity.

Editor’s Choice: Red Meat Has More Good or Bad Effects?

2024-04-06 05:01:00
#Fatin #Shidqia #admits #doesnt #eat #beef #benefits

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The Incredible Health Benefits of Bone Marrow: A Superfood You Need to Add to Your Diet
Health

The Incredible Health Benefits of Bone Marrow: A Superfood You Need to Add to Your Diet

by Chief editor of world-today-news.com
written by Chief editor of world-today-news.com

VIVA Lifestyle โ€“ Bone marrow’s incredible health benefits, from supporting heart health to improving joint function, make it a superfood. Find out more about this nutrient-dense food in the following article. Scroll to read in full, reported from various sources.

Bone Marrow for Health

Maybe not many people know that the benefits of bone marrow for health are extraordinary. The health benefits of bone marrow make this dish popular among non-vegetarians. Currently, bone marrow in particular is becoming popular again in the culinary world.

Some chefs see it as a delicacy, while health enthusiasts praise its superfood status. Here, let’s take a look at the nutritional benefits of bone marrow and discover simple ways to add it to your daily diet.

What is Bone Marrow?

Bone marrow is a chewy and fatty connective tissue that is located right in the middle of bones such as the hip bones, femurs, spine and thighs. It contains special cells called stem cells that turn into red blood cells, white blood cells, and platelets, which play an important role in oxygen transportation, blood clotting, and immune function.

In various dishes, people consume bone marrow from animals such as cows, sheep, caribou and deer. Having a rich, slightly sweet taste and smooth texture, bone marrow is often served with toast or used in soup dishes.

It is a delicious way to support overall health and is tastier for most people than other organ meats such as brain, kidney, heart, or liver.

Bone marrow is usually used to make bone broth, vegetable soups and so on, but can also be used in bread, meat dishes, or other roasted vegetables. The benefits of bone broth for humans are quite large.

The best source is concentrated bone broth, which offers maximum benefits for your health. According to Dr. Ben Carvosso, Doctor of Chiropractic and Owner of MP Nutrition, โ€œWhen comparing bone marrow stock versus consuming bone marrow directly, there are several key factors to consider. Nutrient extraction and concentration are among the most significant.

Bone marrow stocking involves boiling the bones over a long period of time, which can result in the introduction of more concentrated nutrients into the fluid, including collagen, minerals, and healthy fats. This process makes it easier for individuals to consume these important nutrients, which may be more difficult if consuming bone marrow directly.โ€

Nutritional Value of Bone Marrow

  • Calories: 786 kcal
  • Protein: 6,7 gram
  • Fat: 84.4g
  • Iron: 4.5mg
  • Phosphorus: 107mg
  • Thiamine: 0.04mg
  • Niasin: 0,2mg
  • Vitamin A: 240 IU
  • Vitamin A: 240 IU

What are the Benefits of Bone Marrow for Health?

Bone marrow not only makes a delicious addition to a variety of dishes, but also offers many health benefits that contribute to overall well-being. Instead of being curious, dive into the specific benefits of bone marrow for your body below.

  • Building Stem Cells and Repairing Damaged Cells
  • Improves Brain Health
  • Helps Gut Health and Digestion. Bone marrow serves as a valuable source of glycine, a key element in repairing intestinal tissue and improving intestinal health, thereby improving digestion
  • Better Sleep Quality. Additionally, the presence of glycine has been linked to better sleep quality, making this an added benefit of consuming bone marrow.

  • Reduces the Risk of Weight-Related Diseases. A study shows that fatty tissue in the bone marrow contains a hormone called adiponectin. This hormone helps break down fat. It can maintain insulin sensitivity and has been linked to a reduced risk of diabetes, cardiovascular (heart) disease and other obesity-related cancers. High levels of adiponectin are directly related to a reduced risk of developing diabetes and other cardiovascular diseases. The study found that overweight people tended to have lower levels of adiponectin, but levels of the hormone increased as they lost weight.

  • Improves Immune Function. It also contains adiponectin, a protein hormone that helps control inflammation and immune function.
  • Healthy Joints. They increase collagen synthesis in tendons, joints, cartilage, and ligaments, thereby benefiting those with joint-related conditions such as arthritis and osteoarthritis.
  • Reduces Joint Pain. Collagen and gelatin are excellent supplements for improving joint function and reducing joint pain.
  • Reduces Inflammation. Glycine, a protein found in bone marrow, has powerful anti-inflammatory properties and can help reduce chronic inflammation in the body. These anti-inflammatory properties may also have a potential role in preventing cancer and cardiovascular disease. Additionally, conjugated linoleic acid (CLA), another compound in bone marrow, has been shown to lower several markers of inflammation in the blood.
  • Good for Diabetes. Bone marrow is a great addition to the diet, especially for people with diabetes. It contains a rare protein hormone called adiponectin, which plays an important role in lowering the risk of obesity-related cancers, insulin resistance, and diabetes. Ideal adiponectin levels help maintain healthy blood sugar levels and improve insulin sensitivity ().15
  • Improves Skin Health. Collagen, a structural protein important for healthy skin, can be found in bone marrow. Research has shown that supplementing with collagen can improve skin elasticity and hydration.

The conclusion

It is important to note that most of the studies mentioned above were conducted using concentrated supplements containing specific compounds found in bone marrow. More research is needed to determine whether consuming bone marrow itself provides similar health benefits. Even so, adding bone marrow to your diet can be a delicious and nutritious option to support your body’s overall health.

How to Add Bone Marrow to Your Diet?

You can easily find bone marrow in markets, butcher shops, and health food stores. If you are new to bone marrow, choose beef bone marrow. This is a great option because it’s easy to find, the bones are a good size, and you get the added health benefits of beef bone broth. Apart from that, the bone marrow of animals such as caribou, sheep and deer is commonly consumed in various dishes.

2023-12-20 22:20:02
#Amazing #Benefits #Bone #Marrow #Rid #Stubborn #Fat

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