Newly Evolved Genes Orchestrate Cell Division
Researchers Discover How Recent Genetic Players Influence Life’s Fundamental Process
Scientists have uncovered how recently evolved genes control cell division, a crucial process for life. This research reveals that even the most basic biological functions continue to adapt and change over time, with implications for understanding diseases like cancer.
Newly Identified Players
At EPFL, researchers have found that recently evolved genes actively influence how cells divide. This study, led by Romain Forey and Cyril Pulver, examined the role of these genes. They focused on transcription factors, proteins controlling gene activity, and how they affect the cell cycle.
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“We contribute a comprehensive resource regarding human cell cycle gene expression and perturbations, which we hope will be of use to our colleagues worldwide.”
—Cyril Pulver, Scientist
According to the National Cancer Institute, there will be an estimated 2 million new cancer cases diagnosed in the U.S. in 2024 alone (Source).
Deeper Dive into Cell Division
The EPFL team created an extensive atlas of human cell cycle gene activity. By observing these factors, they identified new players regulating various cell cycle phases. Disrupting these factors in cells caused timing issues and problems, disrupting the division.
This research offers new insight into the cell cycle’s complexities and how it relates to health. It may also explain why certain cancers behave differently in humans.
