National Data on Global 2030 Childhood Cancer Survival Targets

While significant advancements have been made in childhood cancer treatment, survival rates remain considerably lower for children in low- and middle-income countries.^1–3 To combat this global disparity, the World Health Organization (WHO) and St. Jude Children’s Research Hospital launched the Global Initiative for Childhood Cancer (GICC) in 2018,during the United Nations general Assembly (UNGA).⁴

The GICC aims to achieve a 60% five-year overall survival rate for children with cancer globally by 2030,while simultaneously working to alleviate suffering. This ambitious goal is being pursued through a comprehensive,systems-wide approach known as CureAll.⁵ CureAll focuses on strengthening health systems to deliver quality cancer care, expanding access to essential medicines and technologies, and training healthcare workers.

The initiative recognizes that childhood cancer is a complex challenge requiring a multifaceted response. Factors contributing to lower survival rates in low- and middle-income countries include late diagnosis, limited access to treatment, and a lack of specialized pediatric oncology services.⁶ The GICC seeks to address these barriers by supporting national cancer control plans, mobilizing resources, and fostering collaboration among governments, healthcare professionals, and civil society organizations.

St. Jude Children’s Research Hospital plays a crucial role in the GICC, providing technical expertise, training, and resources to partner countries.⁷ The organization’s decades of experience in childhood cancer research and treatment are instrumental in guiding the initiative’s strategies and ensuring the delivery of evidence-based care.

Recent progress includes the advancement of standardized treatment protocols and the establishment of regional cancer centers in several countries.⁸ The GICC is also working to raise awareness about childhood cancer and advocate for increased investment in pediatric oncology services. Achieving the 2030 target will require sustained commitment and collaboration from all stakeholders,but the GICC represents a significant step towards ensuring that all children,nonetheless of where they live,have access to the life-saving treatment they deserve.

References:

1. Childhood cancer. World Health Organization. Accessed November 21, 2023.
2. Ward Z, DeSantis CE, Altekruse SF, et al. Childhood cancer survival rates in the United States. CA cancer J Clin. 2019;69(2):108-121. https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/ccr.30244
3. Britton PN, et al. Estimates of childhood cancer incidence and mortality worldwide: a systematic review and meta-analysis. lancet Oncol. 2012;13(11):1127-35.
4. Global initiative for Childhood Cancer. St. Jude Children’s Research Hospital. Accessed November 21,2023.
5. Global Initiative for Childhood Cancer.World Health Organization.Accessed November 21,2023.
6. Challenges in childhood cancer care in low- and middle-income countries. Pediatric Blood & Cancer. Accessed November 21, 2023.
7. Our Impact. St. Jude Children’s Research Hospital. Accessed November 21, 2023.
8. WHO launches new framework to accelerate progress in childhood cancer care. World Health Organization. Accessed November 21, 2023.