Genetically Engineered Mice Proposed as Lyme Disease Solution for Nantucket
Nantucket,MA – Scientists are proposing a novel approach to combatting Lyme disease on Nantucket Island: genetically engineered mice. The plan,detailed in reporting by 60 Minutes and CBS News,aims to interrupt the lifecycle of the disease-carrying ticks by introducing mice with a natural immunity,perhaps reducing the risk of infection for both residents and visitors.
Lyme disease is a growing public health concern,with cases steadily increasing across the United States,notably in the northeast. Nantucket, a popular vacation destination, faces a disproportionately high risk due to its dense tick population. The proposed intervention could offer a important breakthrough in controlling the spread of the disease, but also raises ecological questions that researchers are working to address before any widespread implementation.
The project centers around modifying mice to lack a protein that ticks need to feed,effectively making them resistant to Lyme disease. Sam Telford, a scientist involved in the research, explained the potential ripple effect: “But then there’s a whole food chain that might depend on these mice that would be impacted.”
Dr. Timothy Lepore, a physician considering delaying retirement, supports the research but emphasizes the need for thorough ecological assessment. As an avid falconer,Lepore is particularly concerned about potential unintended consequences for the island’s ecosystem. “I want more testing done to ensure there won’t be unintended consequences,” he stated.
Researchers plan to begin with a small field trial on a private island to study the ecological impacts before considering any experiments on Nantucket itself. Kevin Esvelt, another scientist on the team, acknowledged the inherent risks of altering nature. “But, conversely, I’m not terribly fond of Mother Nature, if she’s gonna give my kids disease,” Esvelt said. “All of technology is saying to Mother Nature, ‘You’re gorgeous. And we appreciate you very much and we need to conserve you. But we’re not always happy with the way things work, naturally. and so we’re going to change it.'”
The proposal requires approval from both federal and state regulators. CBS News’ Dr. Jon LaPook reported on the story, highlighting the complex considerations surrounding this innovative approach to Lyme disease control.
