Early Antibiotic Use Linked to Children’s Chronic Risks
LONDON — May 3, 2025 — A recent study published in the Journal of Infectious Diseases found that early antibiotic use in children is associated with a higher risk of developing chronic conditions. Researchers examined over a million children’s health records in the UK from 1987 to 2020, discovering links to allergic conditions and intellectual disability. The findings highlight the need for judicious antibiotic prescribing, suggesting parents and physicians review treatment options. For further insight, consider consulting a medical professional.
Early Antibiotic Use Linked to Increased risk of Chronic Conditions in Children
A new study suggests a potential link between early antibiotic exposure in children adn an increased risk of developing certain chronic conditions later in life. The research, published in the Journal of Infectious Diseases, examined the health records of over 1.1 million children in the united Kingdom from 1987 to 2020.
Key Findings: Associations with Allergic and Neurodevelopmental Conditions
- Allergic Conditions: Early antibiotic exposure showed positive associations with asthma (hazard ratio [HR], 1.24), food allergy (HR, 1.33), and allergic rhinitis (HR, 1.06).The strength of these associations increased with multiple courses of antibiotics.
- Intellectual Disability: A dose-dependent relationship was observed between early-childhood antibiotic exposure and intellectual disability.Children receiving five or more courses of antibiotics had a significantly higher hazard ratio (HR, 1.73; sibling-matched: HR, 2.79) compared to those receiving one to two courses.
- No Critically important Associations: The study found no significant associations between early antibiotic use and conditions such as celiac disease, inflammatory bowel disease, juvenile idiopathic arthritis, psoriasis, type 1 diabetes, attention-deficit/hyperactivity disorder, autism spectrum disorders, or anxiety.
Did You Know?
The human gut microbiome, which is significantly impacted by antibiotic use, plays a crucial role in immune system development and overall health. Disruptions in the microbiome during early childhood may have long-lasting effects.
Expert Perspective: Judicious Use of Antibiotics
The study underscores the importance of careful antibiotic prescribing practices,especially for young children. According to Dr. Daniel B. Horton from Rutgers University,
Antibiotics play a critical role in combating bacterial infections, but physicians should be judicious when prescribing antibiotics to children under 2, as frequent use may affect long-term health outcomes.Dr. Daniel B. Horton, Rutgers University
Pro Tip:
Parents should discuss the necessity of antibiotics with their pediatrician and explore alternative treatments when appropriate. Probiotics may help restore the gut microbiome after antibiotic use, but consult with a healthcare professional before starting any new supplements.
