Nashville’s Opry House will host the second annual Band As One Nashville Concert for the Cure on March 22, 2026, benefiting the Susan G. Komen Foundation, organizers announced February 2, 2026.
Country music star Trisha Yearwood will headline the event, which aims to raise funds for breast cancer patient services and awareness. Joining Yearwood will be Ashley McBryde, Charles Kelley, War & Treaty, Lukas Nelson, Rissi Palmer, Hailey Whitters, and The Band Loula, according to a statement from Susan G. Komen.
The concert series was established in response to rising breast cancer diagnoses. The American Cancer Society estimates that 316,950 women were diagnosed with breast cancer in 2025, a slight increase from the 310,720 diagnoses in 2024. Projections indicate that number will climb to over 321,000 in 2026. While the number of deaths is expected to decline slightly – from 42,250 in 2024 to 42,170 in 2025 – the disease remains a significant health concern, affecting one in eight women in the U.S. Over their lifetime.
“I am eager to join forces with Komen for a second year to raise awareness for breast cancer,” Yearwood said in a statement. “I know so many people that have been impacted by this disease, and wait to once again lend my voice to Band As One Nashville and share the stage with so many other amazing artists to make an impact through music.”
Joshua Daniel, Senior Director of Entertainment Engagement and Events at Susan G. Komen, emphasized the growing impact of the concert. “This event continues to grow in reach, energy and impact,” Daniel said. “We’re deeply grateful to the artists who are lending their voices and hearts to this cause.”
The inaugural Band As One Nashville Concert for the Cure, held March 26, 2025, at the Ryman Auditorium, featured Sheryl Crow, Keith Urban, and Lainey Wilson among its performers. The 2026 event marks an expansion of the concert series, moving to a larger venue at the Opry House.
