Nasal Sprays Show Promise in Blocking COVID-19 and Common Cold viruses
Mineola,NY – New research suggests nasal sprays could offer a important defense against respiratory infections like COVID-19 and the common cold,with studies exploring both antiviral gels and antihistamine-based solutions. Scientists are investigating methods to create an immune response directly within the nasal passages, potentially preventing viruses from taking hold and spreading.
While existing preventative measures like vaccines remain crucial, these nasal approaches offer a potential additional layer of protection, particularly as new variants emerge and seasonal illnesses circulate. The findings could be especially impactful for individuals in high-risk settings or those seeking to minimize illness disruption. Researchers emphasize that further study is needed to determine optimal usage and long-term effectiveness.
Harvard Medical School researchers last year developed a gel-like nasal spray that demonstrated nearly 100% effectiveness in blocking viruses from infecting the noses of mice and a 3D model of the human nose. However, the gel requires reapplication to maintain its protective effect, remaining effective for up to eight hours, according to Dr. Michael Spearman.
Another avenue of research focuses on azelastine, an antihistamine. Studies indicate sustained use is necesary for protection, and researchers suggest it could be utilized before entering “high-risk settings, such as large gatherings or travel.” The optimal frequency and duration of use are still under investigation.
Dr. Spearman recently led the first U.S.human clinical trial of a nasal COVID-19 vaccine, released in July. The trial,involving 61 participants,showed those receiving higher doses of the spray were substantially less likely to experience COVID-19 symptoms. A larger study is planned to confirm these results.
“If you do that, then whenever the virus comes around, your immune cells just take care of it, and ideally, you’d prevent the virus from then getting into the lung or getting in anywhere else where it would make you sick,” Spearman said, highlighting the potential of generating an immune response within the nose.
