Jena University Hospital Advances Research at the Immunology-Brain Interface
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Published: October 26, 2023
The Critical Role of Synapses in Neurological Health
The human nervous system comprises approximately 100 billion nerve cells, each forming thousands of connections with other nerve and body cells. These connections, known as synapses, are basic to the nervous system’s function as a central processing unit. Disruptions to synaptic formation or function can have severe consequences for neurological health.
Establishing Translational Neuroimmunology in Jena
Since 2019, Professor Dr. Christian Geis has led the development of the Translational Neuroimmunology section at Jena University Hospital, with support from the Hermann and Lilly Schilling Foundation. This initiative has positioned the study of neuroimmunology as a key research area within Jena’s neurology department.
A central focus of Professor Geis’s research is autoimmune-related brain inflammation. This condition can manifest in various ways, including psychotic symptoms, epilepsy, and memory disorders, and is characterized by the immune system mistakenly attacking healthy tissues within the central nervous system.
DFG Research Group Synabs Deciphers Disease Mechanisms
The DFG (German Research Foundation) research group Synabs, coordinated by Christian Geis, has made significant progress in understanding the molecular mechanisms underlying various neurological diseases. Their work has identified potential new therapeutic approaches, including the development of a promising therapeutic candidate.
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