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recent research highlights the potential of exercise-induced myokines – signaling molecules released by muscles during physical activity – in combating breast cancer. Studies conducted at the University of Copenhagen, denmark, and the Memorial Sloan kettering Cancer Center in New York City, indicate that myokines can inhibit cancer cell growth and metastasis.
Specifically, myokines like interleukin-6 (IL-6) and brain-derived neurotrophic factor (BDNF) have demonstrated anti-cancer properties in laboratory settings. IL-6, traditionally known for its inflammatory role, appears too have a paradoxical effect in the tumor microenvironment, promoting anti-tumor immunity. BDNF, crucial for neuronal survival, also shows promise in suppressing breast cancer cell proliferation.
While these findings are preliminary, they suggest that regular physical activity could be a valuable adjunct therapy for breast cancer patients and a preventative measure for those at risk. The American Cancer Society recommends at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity exercise per week for overall health, including potential cancer risk reduction.
Researchers emphasize that the type, intensity, and duration of exercise may influence myokine production and, consequently, its anti-cancer effects. Further clinical trials are needed to determine optimal exercise regimens for breast cancer prevention and treatment. The German Cancer Research Center (DKFZ) in Heidelberg is currently involved in studies exploring the impact of different exercise protocols on myokine levels in breast cancer patients.
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