This article discusses a new theory explaining chronic symptoms after viral infections, particularly Long COVID. The core idea is that endothelial dysfunction, specifically the development of “Zombie Endothelial Cells,” might potentially be the primary mechanism behind these persistent issues.
HereS a breakdown of the key points:
The Problem: Patients experience a range of chronic symptoms after viral infections, including fatigue, brain fog, body pain, and coronary artery issues.
The new Theory: Endothelial cells, which line blood vessels, can become “senescent” or “zombie-like” after a virus infection. These cells are not dead but are abnormally functioning.
How Zombie Endothelial Cells Cause Problems:
Abnormal Blood Clots (Microclots): These senescent cells can lead to the formation of small, persistent blood clots that are difficult to break down. These microclots hinder the transport of oxygen and nutrients to tissues.
Chronic Inflammation: Zombie cells attract the immune system and stimulate it in the wrong direction, leading to ongoing low-grade inflammation.
Increased Vascular Permeability: The artery walls become leaky,allowing toxins from the gut to enter the bloodstream,which can affect the brain and nervous system.
Microcirculatory Dysfunction: The density of small blood vessels and circulation decreases, impacting tissue oxygenation and contributing to symptoms like brain fog and anxiety.
Immune-Inflammatory Crosstalk: The zombie cells continuously secrete substances that maintain chronic inflammation and stimulate the immune system.
Gut-Brain Axis Disruption: Leaky blood vessels can worsen the impact of gut toxins on the brain.
Mechanical Changes in Blood Cells: The physical characteristics of red and white blood cells can be altered, affecting blood flow and oxygen delivery.
symptoms Explained: This “zombie blood cell” mechanism is proposed to explain various symptoms like fatigue, dizziness, abdominal pain, and cognitive issues seen in Long COVID and other post-viral syndromes.
Expert Opinion: Asst. Prof. Dr.Surat is cited as stating that “Attached to the orbit, anything is not the same.” (This quote is a bit metaphorical and might refer to how the body’s systems are fundamentally altered).He has reportedly experienced the infection four times.
In essence, the article suggests that the virus doesn’t just disappear; it can leave behind damaged blood vessel cells that continue to cause problems by disrupting blood flow, triggering inflammation, and affecting nutrient delivery throughout the body.
