The Remarkable Health of Maria branyas, a 117-Year-Old
Maria Branyas Morera, who lived to be 117 years old, defied typical age-related decline, maintaining remarkable health well into her advanced years before passing away peacefully in her sleep from natural causes. Despite exhibiting some biological markers of aging – notably extremely short telomeres and blood changes frequently enough preceding cancer - these indicators never manifested as actual diseases. This resilience appears to stem from a unique combination of genetic factors, lifestyle, and potentially, sheer luck.
Research revealed Branyas’ cells behaved as if they belonged to someone approximately 40 years younger, with six different measurement methods indicating an epigenetic age around 80. This suggests a notable disconnect between her chronological and biological age.
A key factor appears to be her genetic makeup. She possessed rare gene variants offering protection against cardiovascular disease and dementia, seven of which were previously unseen in European populations. These genes seemingly functioned synergistically,shielding her from the detrimental effects of aging. Furthermore, her mitochondria - the energy producers within cells – operated with greater efficiency than those found in many younger individuals, likely contributing to her continued mental sharpness and freedom from serious chronic conditions.
Her gut health was also exceptional.Branyas exhibited high levels of bifidobacterium, a beneficial gut bacterium that typically declines with age and often nearly disappears in the very elderly. Her intestinal flora resembled that of a much younger person,a significant advantage given bifidobacterium’s role in inhibiting inflammation. While she consumed three yogurts daily,a potential source of these probiotics,researchers did not establish a definitive causal link.
Branyas’ metabolic profile also mirrored that of a healthy middle-aged person,with low levels of “bad” cholesterol and high levels of “good” cholesterol. Her fat processing was remarkably efficient,described by researchers as one of the best profiles they had ever observed.
Scientists emphasize that Branyas’ longevity and health were likely the result of a complex interplay between genetics, a healthy lifestyle – including a Mediterranean diet – and good fortune. However, the study of her case is significant, offering potential insights into how to promote healthier aging by understanding the mechanisms that allow some individuals to remain biologically young for longer.
