Supplements Spark Health Warnings Over Vitamin B6 Dangers

Regulators Consider Stricter Controls as Nerve Damage Cases Emerge

Concerns are mounting over the safety of common vitamin supplements as a potential nerve condition linked to excessive Vitamin B6 intake gains scrutiny. A proposed regulatory change could reclassify high-dose B6 products, making them accessible only through pharmacists.

New Guidelines for Vitamin B6

Following a case where a man developed peripheral neuropathy from consuming too much Vitamin B6 in supplements, Australia’s Therapeutic Goods Administration is contemplating new rules. An interim decision suggests that products containing over 50mg of Vitamin B6 might require a pharmacist’s prescription.

This potential shift comes as a class action lawsuit is being explored against Blackmores, alleging excessive levels of Vitamin B6 in their products.

Understanding B6 Toxicity

Vitamin B6 toxicity, known as peripheral neuropathy, occurs when the body accumulates excessive amounts of B6 from supplements. Unlike many water-soluble vitamins, B6 is stored in the body, potentially leading to nerve damage.

“We found, certainly with B6, that’s not the case, that it is stored in the body.”

—Dr Terri-Lynne South, GP, dietician and spokesperson for the Royal College of General Practitioners

High B6 levels can impair peripheral nerves, causing symptoms like pain, numbness, tingling, and in severe instances, loss of motor function.

Sources of Vitamin B6

While Vitamin B6 is naturally present in foods like fish, fruits, and vegetables without reported adverse effects, concentrated sources are found in supplements. These include multivitamins, magnesium, zinc, and B-complex formulas, as well as fortified foods like energy drinks and breakfast cereals.

The recommended daily intake is low, around 1mg, making it easy to exceed safe limits, especially with multiple supplements. Vitamin B6 can be listed under various names, including pyridoxine, pyridoxal, and pyridoxamine, complicating accurate intake monitoring.

Recognizing Potential Symptoms

Individuals taking supplements or consuming B6-fortified products should be aware of potential toxicity symptoms. These often manifest as non-specific nerve-related issues like pins and needles, burning sensations, numbness, or balance problems, which can stem from various causes.

Preventative Measures and Advice

Dr South advises vigilance regarding all B6 sources and their varied names. She recommends calculating daily intake and consulting a GP or pharmacist if exceeding 50mg. Even without symptoms, exceeding this daily threshold is discouraged.

The exact B6 dosage that triggers toxicity varies significantly between individuals. A blood test can help determine if symptoms are due to B6 toxicity or another condition.

Globally, the recommended upper limit for Vitamin B6 intake is often cited around 100mg per day, according to the U.S. National Institutes of Health Office of Dietary Supplements. Consistently exceeding recommended levels, even if below 50mg for some, can pose risks.