Wegovy Pill Launch: Key Facts About the New Oral Weight‑Loss Drug

January 30, 2026 Dr. Michael Lee – Health Editor Health

Here’s a breakdown of the key information from the provided text:

* Efficacy: Both the 2.4-mg injectable semaglutide (Wegovy injection) and the 25-mg pill versions of Wegovy show comparable weight loss results. The injection led to an average of 14.4% weight loss, while the pill resulted in 13.9% weight loss.
* Side Effects: The trials indicate that both the pill and injection forms of Wegovy have similar side effects, primarily gastrointestinal issues like nausea, diarrhea, vomiting, and constipation.
* Side Effect Severity: About 75% of Wegovy users experience mild to moderate gastrointestinal symptoms. However, only a small percentage (7-10%) discontinue use due to these side effects.
* Dosage Difference: The pill contains a higher dose of the active ingredient then the injection because it needs to be absorbed through the digestive system.
* Real-World Data: Some real-world data suggests a possibly higher percentage of people may discontinue use due to side effects than observed in the initial trials (links provided for further reading).