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Weekly General Hospital Spoilers: Monica’s Death, Quartermaine Drama & More

by Dr. Michael Lee – Health Editor

General Hospital’s Quartermaine Family Faces Loss as Monica Quartermaine Passes

Port Charles, NY​ -‍ September‍ 12, 2025 ‌ – Longtime General Hospital matriarch Monica Quartermaine will pass away during the week⁢ of September 15-19, prompting grief and reflection from her family. The storyline ⁢unfolds as a result of ​actor Leslie Charleson’s ongoing health challenges, which have limited her appearances on the show for years.

Monica’s recent frailty has been a recurring‍ theme on the show, stemming from Charleson’s inability to film consistently. Her final scenes ​aired in December 2023, featuring a poignant reunion with her daughter Tracy (Jane Elliot) upon Tracy’s return to Port Charles.⁤

The upcoming episodes will center on ‌the Quartermaine family’s mourning.Despite their often-strained relationship, Jason and Tracy will share a moment of remembrance for⁢ their mother.⁢ Jason will later grapple with regrets over ​time spent away from Monica,while Elizabeth ⁢(Rebecca Herbst) will‌ be tasked with delivering the news to Drew (Cameron Mathison).

Elsewhere in Port Charles, storylines will include Kai (Jens Austin ⁣Astrup) making an alarming discovery, and Emma (Braedyn Bruner) and Gio (Giovanni Mazza) receiving⁢ distressing news related ⁢to ‍the ‍missing Outback. ‍Britt (Kelly Thiebaud), having‍ revealed her faked death to⁤ her ⁣mother, will confront Obrecht before experiencing a⁤ tense encounter later in the week.

This story was originally reported on⁣ Soap Hub on september 12, 2025.

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