Childhood Virus Linked to Increased Dementia Risk, New Research Suggests
RIO DE JANEIRO, BRAZIL – A common virus most peopel contract in childhood – varicella-zoster virus (VZV), which causes chickenpox – may significantly increase the risk of developing dementia later in life, according to a recent study. The research highlights a previously underestimated connection between past viral infections and long-term neurological health, prompting calls for increased preventative measures.
While a definitive causal link remains under inquiry, the study suggests that repeated reactivations of VZV, even without noticeable symptoms, can contribute to cognitive decline. The virus lies dormant in nerve cells after the initial chickenpox infection and can reactivate as shingles.Researchers hypothesize several mechanisms at play, including the virus’s ability to infect nerve cells causing inflammation, chronic inflammation from frequent reactivations leading to neuronal and vascular damage, and a cumulative impact from severe or recurrent shingles episodes.
The study, based on observational data, found an association – but does not prove causation - between VZV reactivation and dementia. Experts emphasize the need for further research to confirm these findings and determine if preventing VZV reactivation can effectively reduce dementia risk.
Currently, preventative measures include herpes zoster (shingles) vaccination, particularly for elderly individuals and those at high risk, rapid treatment of shingles episodes to minimize complications, and maintaining overall immune health through management of chronic diseases. The findings underscore the importance of considering viral health as a relevant factor in lifelong brain health,demonstrating that VZV’s impact extends beyond a dermatological disease.
