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Title: Olanzapine LAI Safety Data & Schizophrenia Treatment Options

by Julia Evans – Entertainment Editor

Teva Pharmaceuticals Presents Promising New Data for Schizophrenia Treatments

San Diego, CA‍ – September‍ 21, 2025 – Teva Pharmaceuticals today announced encouraging findings from its schizophrenia medication portfolio presented at ⁢the 2025 Psych‌ Congress Annual Meeting in ⁢San Diego. The data highlights potential advancements ⁤in ​both safety and patient care for ‍individuals⁤ living with this complex mental‌ health ⁣condition.

Key findings ​include long-term safety data from ⁤the completed Phase 3 SOLARIS trial⁣ evaluating olanzapine LAI (TEV-‘749), ‌a novel once-monthly, long-acting injectable (LAI) ⁣subcutaneous formulation of olanzapine. Notably,the ⁣trial demonstrated no incidence of post-injection delirium/sedation syndrome (PDSS) among participants. This is⁣ a meaningful finding, as PDSS can be a concerning side effect with⁣ some antipsychotic medications. ⁢ Olanzapine LAI ⁤represents a potential first-of-its-kind long-acting olanzapine‌ treatment‌ option.

In addition, new data on UZEDY®, a risperidone extended-release ⁢injectable suspension⁣ administered​ subcutaneously every one to⁤ two ⁣months, ⁢showed a​ statistically significant association with a shorter length of hospitalization compared to patients receiving ⁤a once-monthly intramuscular injection of Invega Sustenna®. It’s significant to note that‍ this analysis did not evaluate efficacy, safety, or other clinical outcomes ⁣- ‌only length of hospital‌ stay.

“These presentations underscore Teva’s commitment to developing innovative treatment options ⁢for individuals with‍ schizophrenia,” said a Teva spokesperson.”We ‍are encouraged by these‌ findings and believe they represent‌ a step forward in improving the lives⁤ of ⁤patients.”

The ‌data presented at Psych Congress⁤ builds on Teva’s ongoing research into long-acting injectable antipsychotics, which ‍aim to⁣ improve medication adherence and overall patient outcomes.

Source: https://www.globenewswire.com/de/news-release/2025/09/21/3153528/0/en/New-Long-term-Safety-Data-from-the-Completed-Phase-3-SOLARIS-trial-Support-the-Potential-of-Olanzapine-LAI-TEV-749-as-the-First-Long-Acting-Olanzapine-Treatment-Option-for-Schizoph.html


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