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Health

Sepsis Diagnosis Delays Pose Urgent Safety Risk: HSSIB

by Dr. Michael Lee – Health Editor June 27, 2025
written by Dr. Michael Lee – Health Editor

Sepsis Diagnosis Delays Still Endanger UK Patients

A new report from the Health Services Safety Investigations Body (HSSIB) spotlights ongoing risks to NHS patients because of late or missed sepsis diagnoses. The independent body reviewed cases, revealing problems that impact patient care and outcomes across England’s healthcare system.

Serious Concerns Raised

The HSSIB warns that the tardy diagnosis of sepsis continues to be a significant and urgent patient safety concern for NHS patients. The report, examining three specific cases, reveals instances where patients suffered severe harm or even death due to delayed or incorrect sepsis diagnoses. These findings highlight clinicians’ persistent challenges in promptly identifying sepsis.

Issues in Patient Care

The HSSIB’s report pinpointed ten areas needing improvement. These recommendations, based on the reviewed cases, have broader implications for the NHS. The issues include inconsistent referral paths, communication gaps, and failure to spot early warning signs such as new-onset confusion or suspected infection.

“These reports show a consistent pattern of issues around the early recognition and treatment of sepsis,”

—Melanie Ottewill, Senior Safety Investigator at the HSSIB

One critical aspect is the recognition of sepsis symptoms, which vary greatly. The report also indicates that timely treatment hinges on swift diagnosis. The UK Sepsis Trust states that around 48,000 deaths are linked to sepsis each year in the UK. The report emphasizes that listening to families who express concerns about their loved ones is vital.

Challenges in Diagnosis

The cases investigated involved patients with various infections, including urinary tract infections, abdominal pain, and diabetic foot infections. Two of the patients tragically died. The third faced amputation and a lengthy recovery period. The report stresses that there isn’t a single reliable diagnostic tool for sepsis.

For example, in one case, a lack of consistent referral processes and limited information exchange between hospitals caused delayed diagnosis. Another revealed that a direct escalation route for deteriorating patients was missing, and nurses hesitated to start a sepsis screen without confirmed infection signs.

The Sepsis Alliance has reported that early recognition and treatment of sepsis can significantly improve patient outcomes, reducing mortality rates by as much as 50%. (Sepsis Alliance Stats)

Need for Standardized Treatment

Dr. Ron Daniels, founder and chief medical officer of the UK Sepsis Trust, underscored the urgency of prompt diagnosis and treatment. He also called for a standardized treatment plan, a “sepsis pathway,” to ensure that patients receive optimal care from initial symptoms to diagnosis.

Annie Lennon is a medical journalist.

June 27, 2025 0 comments
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Health

Epilepsy Medications Drive Adverse Pregnancy Outcomes

by Dr. Michael Lee – Health Editor June 25, 2025
written by Dr. Michael Lee – Health Editor

Epilepsy Drugs in Pregnancy Linked to Perinatal Risks

Study Reveals Antiseizure Medications, Not Epilepsy Itself, as Primary Culprit

A recent study highlights the increased odds of adverse perinatal outcomes linked to maternal epilepsy. However, the research pinpoints prenatal exposure to antiseizure medications (ASMs) as the main driver of these challenges, offering crucial insights for expectant mothers and healthcare professionals.

Study Methodology Unveiled

Researchers undertook a retrospective population-based cohort study. They examined national health data from Scotland spanning from 2009 to 2021. The study encompassed a total of 629,200 pregnancies. Of those, 2022 involved women with epilepsy, while the remaining 627,178 pregnancies were in women without the condition.

Maternal epilepsy was identified via International Classification of Diseases, Tenth Revision codes. These codes were pulled from pregnancy records or hospital admissions within two years before the estimated conception through the pregnancy. The analysis focused on exposure to ASMs.

Exposure to ASMs was defined as any medication dispensed 30 days before the estimated conception until the pregnancy’s end. The study’s primary aim was to assess the connection between maternal epilepsy and adverse perinatal outcomes. Additional focus was given to effect estimates for exposure to specific ASM monotherapies.

Key Findings and Outcomes

Compared to women without epilepsy, those with the condition displayed increased odds of induced labor (aOR, 1.17; 95% CI, 1.02-1.34) even after adjustments for exposure to ASMs. Prenatal exposure to ASMs was linked with greater odds of preterm birth (aOR, 1.47; 95% CI, 1.25-1.74), induced labor (aOR, 1.38; 95% CI, 1.25-1.52), and NICU admission (aOR, 1.54; 95% CI, 1.33-1.78).

Valproate monotherapy showed the strongest link with congenital conditions (aOR, 3.91; 95% CI, 2.36-6.49), with carbamazepine monotherapy following closely behind (aOR, 1.90; 95% CI, 1.16-3.10).

“Maternal epilepsy is associated with many adverse perinatal outcomes, but most are driven by prenatal ASM exposure. We postulate that joint comprehensive care between obstetricians and epileptologists or other specialists who prescribe ASMs could improve perinatal outcomes,”

—The Study Authors

A 2023 report by the Centers for Disease Control and Prevention indicates that about 3.4 million women aged 15–44 years in the United States reported having epilepsy or seizures. (CDC)

In-Depth Analysis and Implications

The study, led by Paolo Pieirino Mazzone of the Muir Maxwell Epilepsy Centre, University of Edinburgh, emphasizes the critical role of ASMs. This highlights the need for a combined approach in the management of pregnant women with epilepsy.

The study was published online on June 16, 2025, in Epilepsia.

Limitations and Disclosures

The study’s limitations include an inability to consider epilepsy specifics. These include the aetiology, type/syndrome, or seizure frequency/severity. It also did not cover the duration or trimester of ASM dispensation. The reasons for ASM use apart from epilepsy weren’t investigated.

The study did not receive external funding. One author reported receiving consultant, lecture, and/or conference-attendance fees. Another author reported external funding support unrelated to the study.

This study underscores the importance of carefully evaluating ASM use during pregnancy. The findings underscore the need for collaborative care between obstetricians and neurologists to safeguard both the mother and child’s health.

June 25, 2025 0 comments
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Health

Serplulimab Approved: New Hope for Small Cell Lung Cancer Patients in UK

by Dr. Michael Lee – Health Editor June 24, 2025
written by Dr. Michael Lee – Health Editor

UK Approves First Anti-PD-1 Monoclonal Antibody for Aggressive Lung Cancer – A Breakthrough in Treatment

London, UK – June 24, 2025 – In a landmark decision offering new hope to patients, teh Medicines and Healthcare products Regulatory Agency (MHRA) has approved serplulimab (Hetronifly, Henlius) as a treatment for adults with extensive-stage small cell lung cancer (ES-SCLC) [[1]]. This allows the body’s immune system to more effectively recognize and destroy malignant cells – a significant improvement over traditional chemotherapy alone.

Treatment Protocol

The therapy is administered intravenously every three weeks, in combination with standard chemotherapy drugs carboplatin and etoposide [[1]], [[1]]. Treatment will continue as long as the patient demonstrates clinical benefit.

MHRA statement

“As the first and onyl anti-PD-1 monoclonal antibody approved in the UK for small cell lung cancer, this marks an crucial new treatment option for patients,” stated Julian Beach, interim executive director of healthcare quality and access at the MHRA

June 24, 2025 0 comments
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Health

CKD Tied to Depression Risk, More So in Young Patients

by Dr. Michael Lee – Health Editor June 19, 2025
written by Dr. Michael Lee – Health Editor

Kidney Disease Patients Face Elevated Depression Risk

A recent study indicates a significant link between chronic kidney disease (CKD) and an increased likelihood of depression needing treatment, particularly among younger individuals. This finding underscores the importance of mental health considerations in CKD management.

Depression Risk Soars with Kidney Disease

Individuals diagnosed with CKD exhibited a 2.6-fold higher chance of experiencing depression requiring antidepressant intervention compared to those without the kidney condition. Notably, this heightened risk was most pronounced in patients under 60 years old.

Interesting findings on CKD and depression…

— World Today News (@worldtodaynews)
April 12, 2024

Researchers examined data from primary care practices across Germany, spanning from 2005 to 2022. The study included over 165,000 patients, with a mean age of 71.6 years, and carefully matched them with control subjects without CKD to assess the association. The research excluded those with pre-existing conditions like schizophrenia or mood disorders.

“The 10-year cumulative incidence of depression and depression followed by an antidepressant prescription was significantly higher in patients with CKD than in those without.”

—Andreas Kommer, University Medical Center of the Johannes Gutenberg University

According to the CDC, roughly 28.8% of adults in the U.S. with chronic kidney disease also experience symptoms of depression (CDC 2024).

Study Methodology and Findings

The study tracked the occurrence of depression diagnoses within a decade following a CKD diagnosis, along with antidepressant prescriptions. The strongest link was seen in the under-60 age group, which showed a more than sixfold increase in risk.

The most commonly prescribed antidepressants in both groups were mirtazapine and citalopram. Other medications, including opipramol, amitriptyline, and escitalopram, were also frequently used.

Implications for Treatment

The authors suggest that while routine depression screening might not be necessary for all CKD patients, heightened awareness is crucial, especially for younger individuals. This emphasizes the need for tailored mental health care.

June 19, 2025 0 comments
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Health

GMC Social Media Rules: Should Doctors Be Regulated Online?

by Dr. Michael Lee – Health Editor June 18, 2025
written by Dr. Michael Lee – Health Editor

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Navigating the Murky Waters: The Evolving Role of Doctors on Social Media

Table of Contents

  • Navigating the Murky Waters: The Evolving Role of Doctors on Social Media
    • The GMC’s Updated Guidance on Social media
    • The Fraught Landscape of Online Discourse
    • The Ethical Implications of Free Speech for Doctors
    • The Value of Dissent and critical Engagement
    • The Role of Physician Associates
      • Key Considerations for Doctors on Social Media
    • The Ancient Context of Medical Ethics and Public Discourse
    • Frequently asked Questions About Doctors and Social Media

The digital age has transformed how professionals communicate, and doctors are no exception. Once confined to hospital corridors, medical opinions now circulate globally via social media. This shift presents both opportunities and challenges,particularly concerning professional conduct and the spread of information.

The GMC’s Updated Guidance on Social media

In January 2024, the General Medical Council (GMC) released updated guidance titled “Using Social Media as a Medical Professional.” This document emphasizes maintaining professionalism, upholding patient trust, and establishing clear boundaries online. A central tenet advises against using social media to abuse, discriminate, bully, harass, or deliberately target any individual or group.

Implementing this principle raises complex questions. Where does legitimate critique end and perceived harassment begin? Is a doctor publicly challenging unsafe NHS working conditions engaging in necessary advocacy or crossing a line by targeting leadership? Are discussions about physician associates constructive criticism or professional bullying? The GMC offers limited clarity, placing doctors in ethically ambiguous territory.

Did You Know? The Federation of State Medical Boards (FSMB) offers resources on social media and professionalism for medical boards and physicians in the United States.

The Fraught Landscape of Online Discourse

Social media has become an increasingly fraught space for healthcare professionals. Platforms like X are rife with disputes among colleagues, administrators, and the GMC itself. The ongoing debate around physician associates has further inflamed tensions, with allegations ranging from misinformation and professional gatekeeping to outright bullying. While the GMC has acknowledged the increasingly toxic tone of online discourse, its response has largely been limited to expressions of concern rather than decisive action.

This situation raises a broader question: Should the GMC regulate physicians’ conduct on social media? Some argue that professionalism extends beyond clinical settings and that behavior inconsistent with medical ethics undermines public trust. Others view such oversight as overreach, contending that physicians retain the right to express personal views outside of work.

The GMC faces a delicate balancing act. Excessive enforcement risks accusations of censorship and stifling free expression. Insufficient enforcement, however, may undermine its authority as a regulator. The power of professional regulation extends beyond legal authority, including reputational impact. A doctor facing a tribunal over an online post may endure formal inquiry,public scrutiny,and reputational damage.

The Ethical Implications of Free Speech for Doctors

The debate often centers on free speech, but this simplifies a complex moral discussion. Doctors occupy a privileged epistemic position. their speech carries what can be referred to as *epistemic weight*. When doctors speak, people listen and often shape their actions in response. During the COVID-19 pandemic, doctors who spread misinformation misled millions precisely becuase they were trusted by the public.

Ethical analysis concludes that doctors, by virtue of their training and the trust they hold, bear a higher moral burden. Their views must meet a threshold of intellectual honesty and evidential rigor. Understanding the hierarchy of evidence and the scientific method is crucial.

Pro Tip: always verify information from multiple reputable sources before sharing it online, especially when it concerns health-related topics.

The Value of Dissent and critical Engagement

It’s crucial to avoid equating all nonconforming speech with danger. History is filled with figures who challenged prevailing consensus and were later vindicated, such as Ignaz Semmelweis and Gregor Mendel. What separates these figures from conspiracists is not *what* they challenged but *how* they did it. Engaging critically with evidence, welcoming scrutiny, and embracing the scientific process are vital.

If the GMC wishes to guide online professionalism without censorship, it must distinguish between these types of speech. However, even well-intentioned guidance can become irrelevant in the context of social media. Social media is not a neutral forum; its algorithms do not select for truth. Instead,it is an attention economy optimized for outrage,tribalism,and performance.

Platforms like X reward impulsiveness and reactivity over reflection and deliberation. Can professionalism be meaningfully maintained within this space, given social media’s design to fuel hyperbole and outrage?

The Role of Physician Associates

The debate surrounding physician associates (PAs) has become a particularly contentious area of discussion on social media. Concerns have been raised about the potential for misinformation and professional gatekeeping, while others have accused critics of outright bullying. This highlights the challenges in fostering constructive dialogue about evolving roles within healthcare.

Aspect Challenge potential Solution
Misinformation Rapid spread of inaccurate health information Promote evidence-based communication and critical thinking
Professional Boundaries Blurring lines between personal and professional conduct Clear guidelines and training on social media use
Online Harassment Targeting of healthcare professionals with abuse Enforcement of platform policies and support for victims

Key Considerations for Doctors on Social Media

  • Maintain Professionalism: Adhere to ethical guidelines and avoid behavior that could undermine public trust.
  • Verify Information: Ensure accuracy and reliability before sharing health-related content.
  • Engage Respectfully: Foster constructive dialogue and avoid personal attacks or inflammatory language.
  • Protect Patient Privacy: Do not share confidential patient information or discuss identifiable cases online.

What steps can individual doctors take to promote responsible social media use? How can medical organizations better support their members in navigating these challenges?

The Ancient Context of Medical Ethics and Public Discourse

The intersection of medical ethics and public discourse has a long and complex history. From the early days of medicine, physicians have grappled with the tension between their professional obligations and their right to express personal opinions.The rise of social media has amplified these challenges, creating new opportunities for doctors to engage with the public while also exposing them to increased scrutiny and potential risks.

Historically, medical societies and regulatory bodies have played a crucial role in setting standards for professional conduct and addressing ethical dilemmas. However, the rapid pace of technological change and the global reach of social media have made it increasingly difficult for these organizations to keep pace.As an inevitable result, individual doctors must take greater responsibility for their online behavior and exercise sound judgment in their interactions with the public.

Frequently asked Questions About Doctors and Social Media

What are the potential benefits of doctors using social media?
Social media can enable doctors to educate the public, share important health information, and engage in meaningful conversations about medical issues. It can also provide a platform for advocacy and allow doctors to connect with patients and colleagues.
What are the potential risks of doctors using social media?
Potential risks include the spread of misinformation, breaches of patient privacy, damage to professional reputation, and legal liability. Doctors must be aware of these risks and take steps to mitigate them.
How can doctors protect patient privacy on social media?
Doctors should avoid sharing any information that could identify a patient, including names, dates of birth, medical conditions, or treatment details. They should also be careful about posting photos or videos that could inadvertently reveal patient information.
What should doctors do if they encounter misinformation on social media?
Doctors should correct misinformation in a respectful and professional manner, providing evidence-based information to support their claims. They should also report the misinformation to the social media platform.
How can medical organizations support doctors in using social media responsibly?
Medical organizations can provide training and resources on social media ethics,develop clear guidelines for online conduct,and offer support to doctors who encounter challenges on social media.

Disclaimer: This article provides general information and should not be considered medical, legal, or financial advice. consult with a qualified professional for personalized guidance.

Share your thoughts in the comments below and help us foster a constructive dialogue about the evolving role of doctors in the digital age. Subscribe to

June 18, 2025 0 comments
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