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Understanding Cognitive Decline and Aging: What Science Tells Us and How to Test for Cognitive Perception
Health

Understanding Cognitive Decline and Aging: What Science Tells Us and How to Test for Cognitive Perception

by Chief editor of world-today-news.com February 12, 2024
written by Chief editor of world-today-news.com

Dubai, United Arab Emirates (CNN) – Concerns about age and mental fitness are a recurring theme during the past US presidential elections, and are set to escalate in 2024 as two of the front-runners approach or pass the age of 80.

If he is re-elected next November, US President Joe Biden will remain in the White House until he is 86 years old. While former President Donald Trump will turn 82 years old at the end of his second term.

But what does science tell us about aging and what does a typical level of cognition look like at age 80?

How do we change as we get older?

Dr. Emily Rogalski, a professor of neuroscience at the University of Chicago, explained that cognitive decline is a normal part of healthy aging. In general, cognition peaks in your 30s and then gradually declines over time.

Common changes in thinking as people age include slower recall of words and names, difficulty multitasking, and a slight decrease in attention span, according to the Center on Memory and Aging at the University of California, San Francisco. These skills are part of what scientists call fluid abilities, which decline regularly throughout our lives.

“Fluid abilities are actions like processing speed, attention, and working memory. They all require cognitive competence,” said Dr. Molly Mather, an assistant professor of psychiatry and behavioral sciences at Northwestern University’s Feinberg School of Medicine.

Natural changes occur in the brain as a person ages. Some parts important for learning and other complex mental activities shrink, communication between nerve cells may become less effective, blood flow may decrease, and inflammation may increase, according to the National Institute on Aging.

Dr. Angela Roberts, an assistant professor of communication and computer science at Western University who researches aging and factors in cognitive decline, noted that “being confused with nouns or having difficulty retrieving the nouns, especially if the nouns are similar or if you associate two people together in your mind, “It’s not necessarily something unusual as we get older.”

Although they are frustrating experiences, they do not necessarily indicate a broader problem with perception or memory per se if they occur from time to time, according to Roberts.

Even from day to day, our thinking abilities can change radically, and are affected by factors other than age, such as illness, stress, distraction, and lack of sleep.

Mild cognitive impairment is clinically diagnosed when cognitive difficulties become frequent and fall outside the range of what is considered normal aging.

If these difficulties become so pronounced that they affect everyday abilities such as getting dressed or going to the bathroom, a clinical diagnosis of dementia can be made, according to the Center for Memory and Aging at the University of California, San Francisco.

There are many causes of dementia, but Alzheimer’s disease is the most common among them.

In contrast to “fluid abilities,” some “crystallized abilities” improve with age, and Roberts explained that this includes knowledge that comes from learning and gaining experience, such as learning new vocabulary.

How is cognitive perception tested?

Assessing cognition can be difficult, even for doctors, and they can use several different methods to determine if someone has cognitive problems that fall outside the range of normal aging. Such as assessing any unusual changes in the patient or asking relatives or close friends if they have noticed these changes.

Doctors order brain imaging and other medical tests, such as a blood test, to rule out other factors that can lead to cognitive decline, such as infection or vitamin deficiency. They use cognitive tests, such as the Mini-Mental State Examination, to evaluate performance in different cognitive domains.

As for the mini-mental status test, which consists of 11 questions, patients are asked to remember today’s date and where they are, and to identify three words to remember later after a few minutes. Their attention span is assessed by asking them to spell a word backwards. Additional tasks test language skills, including following commands, repeating words, reading, and writing.

Different aging pathways

Experts say there is great variation in how people age.

“Chronological age does not necessarily reflect biological age,” said Dr. Nir Barzilai, director of the Institute for Research on Aging at Albert Einstein College of Medicine and scientific director of the American Federation for Research on Aging.

Although population-level data link aging to cognitive decline, the actual manifestation of aging is highly variable at the individual level, Rogalski explained.

Rogalski is leading a research study collecting data on “super-elders,” people in their 80s who have brains as sharp as those under 30.

Researchers have been studying the category of “super-elders” to try to understand genetic and environmental protective factors that could help stave off aging.

Through brain scans, they found that the “super-elderly” had more gray matter than ordinary elderly people in areas of the brain responsible for cognitive performance and memory. They also had, on average, larger and healthier cells in the entorhinal cortex, one of the first areas of the brain affected by Alzheimer’s disease.

In terms of lifestyle, “super seniors” tend to report strong social relationships, live active lifestyles, and continue to challenge themselves.

2024-02-12 10:39:14

#cognitive #ability #80yearolds

February 12, 2024 0 comments
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5 Things to Get Rid of in 2024 to Achieve Your Dreams and Goals
News

5 Things to Get Rid of in 2024 to Achieve Your Dreams and Goals

by Chief editor of world-today-news.com January 13, 2024
written by Chief editor of world-today-news.com

Dubai, United Arab Emirates (CNN) – Being an adult, striving to achieve your dreams, and assuming adult relationships and responsibilities, represents a challenge, no matter how old you are. But you can get rid of five things that you have relatively little control over, which may constitute a good start for anything else you want to achieve during the year 2024, and the following years.

Credit: visualspace/E+/Getty Images

1. Stop a subscription or two

Is there anything more important than knowing where your money is spent? There might be recurring charges for, say, a streaming service, a productivity app you no longer use, or a membership you kept that became useless. This exercise reminds you to monitor those small expenses on a regular basis because if you ignore them, they may turn into big expenses.

2. A general inventory of friends

Whoever tells you that friendship is easy is lying to you. Even your favorite people may disappear from your life when the tasks and responsibilities you take on become too much. So make a list of all the people you want to give a lot of love to this year, and rekindle friendships that mean to you during this year. As with anything else, it may take some intentional effort.

3. Learn a new home skill

Credit: Klaus Vedfelt/Digital Vision/Getty Images

No one knows everything. Do you know how to fix a taillight? Change tires? How old are the air filters in your home? When was the last time you cleaned a coffee machine? Do you know how to clean your coffee maker? Where did you put the fire extinguisher? Do you know how to clean dryer ducts, tiles, or seal a small hole in the wall?

The Internet is rich with people waiting to share this knowledge with you, and learning can be really useful. The more you know, the more confident you’ll be, and the less surprised you’ll be the next time you feel a little discomfort.

4. Make time to maintain your mental health

For some reason, we think that adulthood parallels stress in our daily lives. This makes sense because life is stressful. But to be an effective adult who gets things done and has a good relationship with himself, you have to do something to relieve the burden. Allocate yourself just 15 minutes a day to do something that calms you, such as drinking tea, positive self-talk, and stretching. This is all you need to start maintaining your mental health.

5. Identify what interests you

Successful adults have a sense of priority that shapes their choices, from their financial decisions to how they spend their time. It’s okay to have this experience too. But how will you achieve this? What should you focus on? What small steps can you take daily to make this happen? Record how you feel when you think about what you will achieve in the future. Working through this may give you a renewed sense of purpose, which is important not only for success but for living a long and happy life.

2024-01-13 07:40:54
#ways #live #life #adult #year.

January 13, 2024 0 comments
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Health

New Study Reveals Link Between Interrupted Sleep and Memory Problems Decades Later

by Chief editor of world-today-news.com January 10, 2024
written by Chief editor of world-today-news.com

Dubai, United Arab Emirates (CNN) – A new study shows that people who suffer from a lot of interrupted sleep in their 30s and 40s are twice as likely to have problems with memory and thinking, a decade later.

The research was published in Neurology, the medical journal of the American Academy of Neurology, on Wednesday.

In the early 2000s, researchers tracked the sleep quality of hundreds of people through two overnight visits about a year apart, obtaining a total of six nights of sleep per person. Sleep quality was assessed using a wrist activity monitor that tracks the amount of sleep people got during periods of movement to measure sleep fragmentation, or short, frequent sleep interruptions. Participants were about 40 years old, on average, at this stage of the study.

More than a decade later, between 2015 and 2016, the researchers analyzed the cognitive ability of 526 of the same participants through standardized interviews and tests of cognitive ability, including processing speed, executive function, memory and fluency. On average, study participants found they slept about six hours each night, and about a fifth of their sleep time was interrupted.

Overall, people who had fragmented sleep, or spent a greater portion of their sleep hours moving, were more likely to have poorer cognitive scores on all tests.

The study found that among 175 people with more sleep disturbances, 44 had poorer cognitive performance after 10 years, compared to 10 of 176 people with fewer sleep disturbances.

People who slept less or had higher interrupted sleep were significantly more likely to be male, black, have a higher body mass index, and a history of depression or high blood pressure.

Due to the small sample size, researchers were unable to fully investigate potential racial or gender differences. But after adjusting for health and other demographic factors, they found that those with the most disturbed sleep were twice as likely to have worse-than-average scores on a battery of cognitive tests, compared to those with the least disturbed sleep.

Study author Dr. Yue Ling said, “Given that signs of Alzheimer’s disease begin to accumulate in the brain several decades before symptoms appear, understanding the relationship between sleep and cognition early in life is crucial to understanding the role of sleep problems as a risk factor for the disease.” .

Throughout the study, participants were also asked to keep a sleep diary, track bedtimes and wake times, and rate their sleep quality, Ling, an assistant professor of psychiatry at the University of California, San Francisco, explained in a press release. However, objective measures of sleep duration and subjective assessments of sleep quality were not associated with cognition in midlife.

“Our findings suggest that sleep quality, not quantity, is most important for cognitive health in midlife,” Ling said.

People are supposed to sleep between 7 and 10 hours each night, depending on their age. However, the US Centers for Disease Control and Control explained that one in three Americans does not get enough sleep.

Between 50 and 70 million Americans suffer from sleep disorders such as sleep apnea, insomnia, and restless leg syndrome that can disrupt your night’s sleep. The US Centers for Disease Control and Prevention considers this condition a “public health problem,” because disrupted sleep is associated with an increased risk of conditions such as diabetes, stroke, cardiovascular disease, and dementia.

One study conducted in 2021 found that people who routinely reported having difficulty sleeping had a 49% increased risk of developing dementia, while those who often woke up at night and had difficulty returning to sleep were more likely to develop dementia. Dementia by 39%.

A study published in October found that chronic loss of slow-wave sleep, the third stage of sleep during which the body removes unwanted or potentially harmful substances from the brain, may increase the risk of dementia.

“More research is needed to evaluate the relationship between sleep disturbances and cognition at different stages of life and to determine whether critical life periods exist when sleep is most strongly associated with cognition,” Ling said.

“Future studies could open new opportunities for preventing Alzheimer’s disease later in life,” he concluded.

2024-01-09 09:54:36

#Study #Sleep #disturbances #30s #40s #linked #cognitive #decline

January 10, 2024 0 comments
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The World Health Organization is monitoring the BA.2.86 strain and classifies it as “interesting”… What is the reason?
Health

The World Health Organization is monitoring the BA.2.86 strain and classifies it as “interesting”… What is the reason?

by Chief editor of world-today-news.com December 1, 2023
written by Chief editor of world-today-news.com

Dubai, United Arab Emirates (CNN) – The World Health Organization has classified the BA.2.86 coronavirus variant and its mutations as “of concern,” although the risk emanating from this strain, according to what the organization stated, appears low.

The organization had previously tracked this mutant as “under surveillance.”

Other variants also classified as “interesting” are XBB.1.5, XBB.1.6 and EG.5. There are no current variants of concern, which is the highest classification in the organization.

BA.2.86 first appeared in the United States in August, and is considered the third most common variant, causing about 1 in 11 new cases of “Covid-19,” according to the latest update on variant tracking at the US Centers for Disease Control and Prevention. The rate of spread appears to have tripled in the past two weeks, although the growth of the mutant was overestimated in the first few weeks after its appearance, according to the agency’s monitoring.

But if BA.2.86 is not so important, why is WHO updating it?

“We have seen a slow and steady increase in its detection around the world,” Dr. Maria Van Kerkhove, technical lead for COVID-19 at the World Health Organization, explained in a video circulated on social media. She continued: “By describing it as a variant of interest, it helps to strengthen the monitoring of these types of variants around the world, and also stimulates research” to understand whether it causes more severe disease or is more immune evasive.

Slow development

BA.2.86, which some virus watchers called Pirola, sparked a wave of research when it came to the world’s attention over the summer because it shared many of the characteristics that led to the spread of the BA.1 variant, of the original Omicron strain of the coronavirus, and it spread quickly, leading to… Hospitalizations and deaths are rising globally.

With more than 30 mutations in its spike proteins, BA.2.86 was so genetically distinct from previous mutations of the virus that causes Covid-19 that scientists feared it might completely evade vaccine immunity and contribute to another wave of infections.

However, what is puzzling is that BA.2.86 did not follow the same path as Omicron. Some studies have indicated that with the development of all its new mutations, this variant has lost some of its ability to infect our cells, allowing their growth to slow.

Other studies found that it did not completely evade the body’s immunity and that the current “Covid-19” vaccine, which carries instructions on combating the XBB.1.5 mutant, provided some protection from it, which was good news.

But mutant hunters tempered this optimism by warning that the original virus BA.2.86 is still evolving, and one of its variants may recover to become a force to be reckoned with.

Dr. Jesse Bloom, a computational virologist at the Fred Hutchinson Cancer Center in Seattle, USA, pointed out that in fact, BA.2.86 continues to evolve and send more rapid mutations to the world.

Bloom pointed out that work conducted by researchers at Columbia University and China showed that the JN.1 mutant has one change in its genetic code that makes it more able to escape our immune defenses, although the difference is modest: the ability of our antibodies to neutralize the virus has declined by about two times.

However, it seems that this modification was enough to give it a growth advantage over its predecessor.

“In terms of the speed of its spread, what we can see is that the numbers of JN.1 are increasing faster than the original BA.2.86,” Bloom said.

At the same time, the distantly related XBB family of viruses, which now includes several faster and more evasive strains such as HV.1, is expanding its spread.

HV.1 is currently the dominant strain in the United States, according to the Centers for Disease Control and Prevention, and causes illness in about 1 in 3 new cases of COVID-19.

Scarcity of data Make predictions difficult

“A number of countries have seen a rise in cases abroad as BA.2.86 and JN.1 spread,” noted Dr. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota.

In Europe, the disease was linked to many countries, but it did not happen in other countries, so what do we understand from that?

Europe has been considered a good barometer of what the coronavirus might do to the United States, but immunity, behavior and surveillance vary so much from country to country that it is difficult to know what might happen there.

One big problem is the paucity of data, said Dr. Peter Hotez, a pediatric infectious disease specialist at Baylor College of Medicine and Texas Children’s Hospital, who developed a COVID-19 vaccine.

“Knowing what’s going on is harder than it used to be because we’re no longer doing as much surveillance, so we have to rely on forecasts, and a combination of elements like wastewater, hospitalizations, and the percentage of positive cases,” Hotez explained.

However, given the signs we can see, Hotez noted that there is reason for caution in the coming weeks.

Hospitalization rates due to the Corona virus, which had been declining, began to rise again.

According to the US Centers for Disease Control and Control, last week, more than 18,000 Americans were hospitalized due to Covid-19, an increase of approximately 10% from the previous week.

Nationally, coronavirus levels in wastewater have been rising and appear to be increasing, which may herald rising case numbers.

2023-12-01 09:56:21

#World #Health #Organization #monitoring #BA.2.86 #strain #classifies #interesting.. #reason

December 1, 2023 0 comments
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Cabbage…what are its most prominent health benefits to the body?
Health

Cabbage…what are its most prominent health benefits to the body?

by Chief editor of world-today-news.com November 30, 2023
written by Chief editor of world-today-news.com

Dubai, United Arab Emirates (CNN) – Although it is considered among the oldest types of vegetables in existence, cabbage still represents a staple food all over the world.

The Florida Department of Agriculture and Consumer Services (FDACS) explained on its official website that cabbage contains a high percentage of antioxidants.

Eating cabbage can benefit you with:

  • Cancer prevention
  • Preventing heart disease
  • Helping heal wounds because it contains a high percentage of vitamin C, which is a powerful antioxidant

If you are following a strict diet to lose weight, cabbage is distinguished by being the type of vegetable that contains the least calories and fat.

Shopping, preparing and storing

  • Avoid cabbage that has holes. Make sure to smell the pulp when shopping.
  • Whole raw cabbage should be cooled in a plastic bag.
  • Red and green cabbage leaves should be firm and of good colour.

Cooking tips

  • Cabbage can be steamed, boiled, microwaved, stuffed, or eaten raw.
  • Remove any discolored or wilted leaves before cooking.

Earlier, the Saudi Ministry of Health explained, through its official account on the “X” platform, that cabbage is considered among the rich sources of vitamin K.

Adults need about 1 microgram per day of vitamin K per kilogram of body weight.

Symptoms of vitamin K deficiency include:

  • Osteoporosis
  • A defect in blood clotting causes increased bleeding

2023-11-29 09:02:29

#Cabbage…what #prominent #health #benefits #body

November 30, 2023 0 comments
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Work, sport, arts… The mysteries of “flow”, the ultimate concentration
Business

Work, sport, arts… The mysteries of “flow”, the ultimate concentration

by Chief editor of world-today-news.com November 29, 2023
written by Chief editor of world-today-news.com

It is said that he makes you forget time and your immediate environment. That it allows concentration as intense as it is pleasant. That it leads to unbeatable bursts of productivity. A moment of a few tens of minutes, or even a few hours, where everything seems fluid, logical and easy. Her name ? THE flow. A state – sometimes described as quasi-dissociative – in which one finds oneself entirely absorbed by a task. To the point that some people try at all costs to achieve it in order to increase their performance.

And they concept a emerged during the 1970s and remained linked to the sporting field for a long time, it has become popular in recent years, particularly through professional coaches and businesses, who are looking for commercial applications. It is also of interest to the world of research. But although numerous studies have been published on the subject, blind spots remain. “THE flow has been little studied from the point of view of brain activity, in particular because it is not so easy to induce such a mental state inside an MRI”, indicates Corentin Gonthier, professor of psychology at Nantes University, specialist in intelligence.

Sometimes contradictory results, little certainty

Some experiences (carried out using MRIs, electroencephalograms or questionnaires) nevertheless show that the brain activity observed during a state of flow is complex and occurs at several levels, even if there is not a brain area specifically dedicated to it. “It is believed that brain activity decreases in the ‘default mode’ network, that is to say the areas activated when we are not carrying out any particular task. This is why we would then fully engage in work precise, without thinking of anything else,” continues the researcher.

READ ALSO >>How to achieve the state of “flow”? “Effort, silence and concentration”

Studies, which sometimes contradict each other, also suggest that brain activity could either increase or decrease in areas linked to attentional control, which is the ability to regulate one’s cognitive activity for tasks that cannot be solved automatically and which involve complex operations (e.g. maintaining attention on a task while ignoring distractions). This could explain the increased attention we then pay to a specific task or, on the contrary, explain a sort of automatic piloting of the brain. In the event that the flow would be a form of attentional control entirely invested in the task to be accomplished, this would suggest that this process requires cerebral resources usually linked to the perception of time, hence the impression of not seeing the minutes pass.

Should you concentrate for five, ten or thirty minutes to trigger flow?

Apart from these few clues, no one knows precisely what happens inside the brain during flow. Although the sensations associated with the phenomenon are relatively well documented, we do not know exactly how or when it is triggered, or whether it requires concentration for five, ten or thirty minutes. Here again, the experiments that would need to be carried out to discover it turn out to be complex. “The main reason is that reaching this state undoubtedly depends on the people, but above all on the task,” underlines Corentin Gonthier. Then, it remains difficult for researchers to assert, by simple observation, if and when someone “enters into flow“, since it is a subjective state.

READ ALSO >>Emails, alerts, messaging, pop-ups: “multitasking”, this new enemy of the brain

Respondents asked about the duration of the phenomenon could also tend to provide unreliable answers, since the flow goes hand in hand with a changed perception of time. Finally, ask someone to indicate when they enter a state of flow could interfere with the process, since it would distract their attention from the task.

Because it is one of the rare certainties: the flow does not trigger on command, nor in a few seconds. It requires concentration and full attention to the operation to be carried out, but also a pleasure in carrying it out, as well as clear objectives and a difficulty appropriate to the level of skill. Thus, regularly interrupting an activity will prevent the triggering of the flow. The multitasking, which consists of frequently juggling between different actions – working, reading emails, checking email or social networks – probably represents the worst enemy of flow… And “ideal productivity”.

.

2023-11-29 16:15:52
#Work #sport #arts.. #mysteries #flow #ultimate #concentration

November 29, 2023 0 comments
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