Greyโ Hair May Signal Body’s Cancer-Fighting Response, New Research Suggests
TOKYO – Graying hair, long โconsidered a simple sign โof aging, may actuallyโ indicate a natural protective mechanism against cancer, according to a new โstudy published in Nature Cell Biology on February 6th by โฃresearchers atโ the University of Tokyo’s institute โคof Medical Sciences. The research, led by โProfessor Emi nishimura, reveals a link between the loss of pigment in hair andโค theโ body’s โresponseโฃ to damagedโค cells that could potentially become cancerous.
Theโฃ study focused on melanin stem โขcells (McSCs) -โค responsible forโ hairโ color – and their reactionโค to DNA damage โinduced by ultraviolet โB (UVB) radiation or similar chemicals in โคmouse models. Researchers observed โฃthat when McSCsโ sustained damage, โขsome cellsโ initiated โa self-destruction process, haltingโฃ normal renewal. This resulted in the loss of pigment โคand the appearance of gray hair.
However,โ other damaged cells survived, accumulating further damageโฃ and exhibiting characteristics similar to cancer cells. โThis suggestsโฃ that the elimination โขof damaged McSCs through the graying process may prevent the advancement of melanoma,a type of skin cancer.
“It does โขnot mean that gray hair directly preventsโข cancer,” โขProfessor Nishimura clarified, “but if the natural protective mechanism that losesโข the pigment production function does โnot work, the risk ofโ cancer may increase.”
The research team emphasized the importance of proper cellular aging and elimination, cautioning against unproven โprocedures or โคtopical medications marketed to restore hair color, as these could potentially be harmful. “Be careful with procedures or topical medications โfor โขwhich safety or scientific evidence has โขnot been established,โข as thay can be perilous,” Nishimura advised.