prediabetes reversal Possible Within Two Years, Landmark Study Finds
London, UK - November 22, 2025 - A comprehensive new study published today in The Lancet reveals that individuals diagnosed with prediabetes can reverse the condition within two years thru sustained lifestyle changes. The research, tracking over 700 participants, demonstrates notable metabolic improvements achievable through consistent diet and exercise, offering a hopeful outlook for the estimated 374 million people globally living with impaired glucose tolerance.
Prediabetes, a condition characterized by blood sugar levels higher than normal but not high enough to be diagnosed as type 2 diabetes, frequently enough presents no noticeable symptoms. However, left unaddressed, it dramatically increases the risk of developing type 2 diabetes, heart disease, and stroke. This study’s findings are especially timely given the escalating global rates of obesity and sedentary lifestyles, which are primary drivers of prediabetes. Researchers emphasize that proactive intervention-specifically, adopting a healthier lifestyle-can not only prevent progression to full-blown diabetes but actively restore metabolic health.
The two-year study involved participants receiving structured support encompassing dietary guidance focused on reduced calorie intake and increased fiber, alongside a programme promoting at least 150 minutes of moderate-intensity physical activity per week.results showed that 68% of participants achieved normal blood glucose levels and improved insulin sensitivity, effectively reversing their prediabetic status.
“We observed remarkable changes in participants’ metabolic profiles,” stated Dr. Eleanor Reynolds, lead author of the study from king’s Collage London. “The body demonstrates a powerful capacity to recover when provided with the right conditions. Consistent effort with diet and exercise triggers a cascade of positive physiological adaptations.”
These adaptations include improved pancreatic function,enhanced glucose uptake by muscles,and reduced inflammation.The study also highlighted the importance of long-term adherence,noting that participants who maintained their lifestyle changes throughout the two-year period experienced the most considerable and lasting benefits. Researchers are now focusing on identifying strategies to support sustained behavioral change and scaling up these interventions for broader public health impact.