pathology

Cover news reporter Zhang Zheng

In this epidemic, Ms. Yu became the only negative patient in her family, and in order to build up her resistance, she decided to try the new inhaled coronavirus vaccine. At 14:00 on December 27, she arrived at an injection site located in Shawan East Road, Chengdu, and stood in line to be vaccinated with the new inhaled coronavirus vaccine. , Everything is fine. Sweet, I have no adverse reactions. You told reporters that many people came to get vaccinated, some chose intramuscular injection and some chose inhalation. “Mostly, people who’ve been vaccinated three times can inhale it, so some people still can’t inhale it. They feel very fresh about the inhaled vaccine.”

The full name of the new inhaled coronavirus vaccine is the new inhaled recombinant coronavirus vaccine (adenovirus type 5 vector). The dosage is only 1/5 of the dosage form of intramuscular injection. There is no need for intramuscular injection, and people who inoculated the inhalation type react and there is no pain. As for who can inhale and how to inhale, which citizens are concerned about, the cover reporter interviewed the vaccination planning experts of the Sichuan Provincial Center for Disease Control and Prevention.

　　It’s very relaxing without injections

Ms. Yu told reporters that when you arrive at the vaccination site, the doctor will give you a white “milk tea cup” filled with small droplets of the vaccine, and then you will follow the vaccination formula as if you were drinking milk tea: ” Exhale once, inhale twice and hold your breath three times.” There are also people who will help you count to 5, 4, 3, 2, 1. After holding your breath for 5 seconds, she breathes normally and the vaccination is over. In addition to the convenience, many citizens vaccinated on the spot said that the vaccine is indeed a bit “sweet”. “No need for injections, very relaxing.”

So what’s so convenient about an inhaled COVID-19 vaccine? An expert from the immunization program of the Sichuan Provincial Center for Disease Control and Prevention told reporters that the inhalation type is mainly reflected in the vaccination method. The atomized inhalation type of the new crown virus vaccine does not adopts the “injection” method of vaccination, but atomizes the vaccine into tiny droplets. Oral inhalation inoculation into the respiratory tract “simulates the process of the virus that naturally infects the human body. While inducing humoral immunity and cellular immunity, it can also stimulate the respiratory mucosa to stimulate mucosal immunity and provide more protection.

　　Booster immunization for people aged 18 and over

The reporter learned from the vaccination point that in order to be inoculated with the new inhaled corona virus vaccine, three doses of the new corona vaccine must have been injected. At the same time, the experts said: “Currently, this new nebulized inhaled coronavirus vaccine is only used for booster immunization for people aged 18 and over. It is not recommended to vaccinate people aged under 18 and is not used for basic immunization at the moment.”

The inhalation formula of the new corona virus vaccination: “one breath, two breaths, three breaths”. Stage 1: Subject first takes a deep breath (do not exhale into the spray cup); Step 2: Put the mist cup nozzle into your mouth and take a deep breath until there is no mist in the cup; Step 3: Hold your breath for 5 seconds Above (minimum 5 seconds), then breathe normally, the vaccination is finished.

　　Patients with fever should be vaccinated after recovery

Experts said that this vaccine is not administered through the nasal cavity, but is inhaled into the respiratory tract through the mouth. Therefore, if the rhinitis patient is not in the acute attack period and there are no other contraindications to vaccination, he can be vaccinated. Those who have fever or suffer from acute illnesses should be vaccinated again after their body has recovered and there are no other contraindications for vaccination.

According to experts, according to the instructions of the vaccine, the contraindications of inhaling aerosol new coronavirus vaccine include: those who are allergic to the active ingredients of this product, any inactive ingredients, substances used in the production process, or those who have been previously allergic to similar vaccines; Patients who have had severe allergic reactions to vaccines in the past (such as acute allergic reactions, angioedema, dyspnoea, etc.); those with uncontrolled epilepsy and other progressive neurological diseases and those with a history of Guillain-Barre syndrome. People with the above contraindications cannot receive this vaccine.

People with the following conditions should use this vaccine with caution: those with acute illness, acute exacerbation of chronic disease, severe chronic disease, allergic constitution, and fever; those with a history or family history of seizures, epilepsy, encephalopathy, or mental illness; those with history of asthma, Patients with a history of chronic obstructive pulmonary disease and underlying diseases such as pulmonary fibrosis or abnormal lung function.

After being vaccinated with the new aerosol inhaled coronavirus vaccine, you still need to stay in the vaccination unit for 30 minutes.

　　Antibodies develop 1 to 2 weeks after vaccination

The chief expert of the immunization program of the Chinese Center for Disease Control and Prevention said, “Generally, antibodies can be produced within 1 to 2 weeks after vaccination. If a relatively high level of antibodies is to be produced, full immunization (basic immunization) will be approximately 4 weeks after full immunization and booster immunization. After that, the time to produce antibodies is faster and shorter, and the levels of antibodies produced are higher.

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