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New Study Highlights Methodological Considerations for Real-World Evidence in CGRP Monoclonal Antibody migraine Treatment
A recent systematic review published in The Journal of Headache and Pain delves into the critical methodological aspects of real-world evidence (RWE) studies concerning monoclonal antibodies targeting the CGRP pathway for migraine treatment. The research, conducted by Vandenbussche, Pisarek, and Paemeleire, underscores the importance of robust study designs in evaluating the effectiveness and safety of these therapies in everyday clinical practice.
The study, appearing in Volume 24, Issue 1 of the journal, provides a complete analysis of existing RWE studies. It aims to guide future research by identifying best practices and potential pitfalls in the design and execution of such investigations. The findings are crucial for healthcare providers, researchers, and policymakers seeking to understand the real-world impact of CGRP pathway inhibitors, a critically important advancement in migraine management.
Vandenbussche N, Pisarek K, paemeleire K (2023) Methodological considerations on real-world evidence studies of monoclonal antibodies against the CGRP-pathway for migraine: a systematic review. J Headache Pain 24(1):75. https://doi.org/10.1186/s10194-023-01611-3