Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis

Patients with cancer are at higher risk of severe coronavirus infectious disease 2019 (COVID-19), but the mechanisms underlying virus-host interactions during cancer therapies remain elusive. When comparing nasopharyngeal swabs from cancer and noncancer patients for RT-qPCR cycle thresholds measuring acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in 1063 patients (58% with cancer), we found that malignant disease … Read more

[First wave of the COVID-19 pandemic in Navarre, Spain, February-June 2020]

Background: The COVID-19 pandemic was declared in 2020. The shortage of diagnostic tests limited monitoring of the first wave of the pandemic. This study estimates and describes the wave in Navarre (Spain). Methods: Enhanced epidemiological surveillance, seroepidemiological survey estimates and mortality registries were used to characterise the first wave of the COVID-19 pandemic from February … Read more

Randomised trial of first-line bronchial artery embolisation for non-severe haemoptysis of mild abundance

Background: Whereas first-line bronchial artery embolisation (BAE) is considered standard of care for the management of severe haemoptysis, it is unknown whether this approach is warranted for non-severe haemoptysis. Research question: To assess the efficacy on bleeding control and the safety of first-line BAE in non-severe haemoptysis of mild abundance. Study design and methods: This … Read more

Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021

COVID-19 vaccine effectiveness was evaluated in close contacts of cases diagnosed during January-April 2021. Among 20,961 contacts, 7,240 SARS-CoV-2 infections were confirmed, with 5,467 being symptomatic and 559 leading to hospitalisations. Non-brand-specific one and two dose vaccine effectiveness were respectively, 35% (95% confidence interval (CI): 25 to 44) and 66% (95% CI: 57 to 74) … Read more

Hepatitis B virus-associated hepatocellular carcinoma is still a matter of concern in the French Caribbean Island of Guadeloupe

Seroepidemiology of chronic hepatitis B and C in the French Caribbean Island of Guadeloupe. Gelu-Simeon M, Pillas V, Deloumeaux J, Delacroix-Maillard H, Saint-Georges G, Do Amaral L, Borel M, Laurent M, Gordien E, Saillard E. 1000 ice-Simeon et al. BMC Res Notes. 2014 Jan 21;7:55. doi: 10.1186/1756-0500-7-55. BMC Res Notes. 2014. PMID: 24447457 Free PMC … Read more

Obsession with Covid-19 in Peruvian police and armed forces: Validation of the obsession with Covid-19 Scale in Spanish using SEM and IRT models

The study evaluated the psychometric properties of the Spanish version of the Obsession with COVID-19 Scale (OCS) in 214 police and members of the armed forces (Mage = 29.33 years, SD = 11.28). The one-dimensionality and satisfactory reliability of OCS were confirmed with confirmatory factor analysis, Item Response Theory analysis, Cronbach’s alpha, and McDonald’s omega. … Read more

COVID-19 in a cohort of pregnant women and their descendants, the MOACC-19 study

Purpose: The Mother and Child COVID-19 study is a cohort recruiting pregnant women and their children in Cantabria, North of Spain, during COVID-19 pandemic in order to ascertain consequences of SARS-CoV-2 infection on pregnant women and their descendants. This article reports the cohort profile and preliminary results as recruitment is still open. Participants: Three subcohorts … Read more

Does bevacizumab increase joint pain in patients with cancer? Results of the prospective observational BEVARTHRALGIA study

Purpose: The occurrence of arthralgia and myalgia during treatment with bevacizumab (Bev) has been described but not spontaneously reported. We aimed to evaluate the frequency of arthralgia in patients treated with Bev and identify the risk factors. Methods: In this observational prospective study, a self-administered questionnaire was distributed to patients at the initiation of Bev … Read more

A case of infective endocarditis caused by Arthrobacter woluwensis

Eur J Clin Microbiol Infect Dis –. 2021 Jan 11. – doi: 10.1007 / s10096-021-04154-0. Online ahead of print. – Affiliations Expand Affiliations 1 Infectiology, Hospital de l’Archet, Center Hospitalier Universitaire de Nice, Nice, France. [email protected]. 2 Internal medicine, Hôpital de l’Archet, Center Hospitalier Universitaire de Nice, Nice, France. 3 Bacteriology, Laboratory of Medical Biology … Read more