single Exercise session Shown to Inhibit Cancer Cell Growth, New Study Finds
LONDON, UK – September 15, 2025, 09:15 BST – A groundbreaking study published today in teh journal Oncotarget reveals that a single bout of high-intensity interval training (HIIT) can significantly reduce the proliferative capacity of cancer cells. Researchers at the University of Newcastle found that HIIT triggers a systemic anti-cancer immune response, effectively slowing tumor growth in preliminary trials. The findings offer a potentially accessible and impactful adjunct therapy for cancer patients and a preventative strategy for at-risk individuals.
the research addresses a critical gap in cancer treatment, focusing on leveraging the body’s own defenses rather than solely relying on traditional methods like chemotherapy and radiation. Cancer affects millions globally,with approximately 10 million deaths reported in 2020 alone,according to the world Health Institution. While advancements in treatment continue, the search for preventative and supportive therapies remains paramount. This study suggests that incorporating regular, intense exercise could be a powerful tool in that fight, offering a low-cost, readily available intervention with potentially far-reaching benefits. Researchers are now planning larger-scale clinical trials to validate these findings and determine optimal exercise protocols for various cancer types.
the study involved 16 participants with varying cancer diagnoses. Each participant underwent a 30-minute HIIT session consisting of four 3-minute intervals of cycling at 85-95% of their maximum heart rate, interspersed with 3-minute recovery periods. Blood samples and muscle biopsies were collected before and promptly after the exercise session.
Analysis revealed a meaningful increase in circulating natural killer (NK) cells – a type of immune cell crucial for identifying and destroying cancer cells – within just one hour of completing the HIIT workout. Moreover, researchers observed a decrease in levels of proteins associated with cancer cell proliferation. “We were astonished to see such a rapid and substantial impact on the immune system and cancer cell behavior after a single exercise session,” stated Dr. Emma Smith, lead author of the study and a researcher in the Faculty of Medical Sciences at Newcastle University. “These results suggest that exercise isn’t just about physical fitness; it’s a potent modulator of the immune system with direct implications for cancer control.”
The team emphasizes that this research is preliminary and does not suggest exercise as a cure for cancer. However, the findings provide compelling evidence for the potential of exercise as an important component of a comprehensive cancer care plan. future research will focus on identifying the specific mechanisms driving this anti-cancer effect and tailoring exercise prescriptions to maximize benefits for different patient populations.