What are the common symptoms of pediatric hidradenitis suppurativa?

Common symptoms include painful lumps under the skin, often in the armpits, groin, buttocks, and breasts. These lumps can heal slowly, reappear, and lead to tunnels and scarring.

What comorbidities are associated with pediatric hidradenitis suppurativa?

Pediatric HS is often associated with obesity, depression, anxiety, hyperlipidemia, and gut microbiome dysregulation.

How is pediatric hidradenitis suppurativa typically treated?

Treatment for pediatric HS is primarily based on adult protocols and may include topical and oral medications, antibiotics, biologics, and surgical procedures.

Why is early detection of hidradenitis suppurativa important in children?

Early detection is crucial for managing symptoms,preventing disease progression,and addressing associated comorbidities like obesity and mental health issues.

What role do multidisciplinary teams play in managing pediatric hidradenitis suppurativa?

Multidisciplinary teams, including dermatologists, mental health professionals, and other specialists, are essential for providing comprehensive care and addressing the complex needs of pediatric HS patients.

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Q: What is hidradenitis suppurativa (HS)?

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful lumps, abscesses, and scarring, primarily in areas with sweat glands.

Q: Are there specific guidelines for treating hidradenitis suppurativa in children?

currently, there are no specific treatment guidelines for pediatric HS, and management strategies are largely based on adult protocols. More research is needed to develop pediatric-specific guidelines.

Health

Bloated Stomach: Causes, Prevention & What to Do

by Dr. Michael Lee – Health Editor September 15, 2025

written by Dr. Michael Lee – Health Editor

Bloating Causes Social Withdrawal, New Podcast Reveals

Berlin, Germany – September 15, 2025 – A critically important number of individuals are experiencing such severe abdominal bloating that it’s leading to social isolation, according to insights shared on the German podcast Aha – Zehn minuten Alltags-Wissen (Aha – Ten Minutes of Everyday Knowledge). The podcast, produced by Welt, highlights the debilitating impact of persistent bloating on quality of life, with many sufferers avoiding public situations due to discomfort and embarrassment.

The Aha podcast addresses a widespread but often unspoken issue affecting millions. While occasional bloating is common,chronic bloating can signal underlying medical conditions or digestive imbalances.The podcast explains that sufferers are increasingly withdrawing from social activities, impacting their mental wellbeing and overall social engagement. Listeners can access the podcast on Apple Podcasts, Deezer, Amazon Music, or directly via RSS feed, with all episodes available at welt.de/Aha.

September 15, 2025 0 comments

Health

Ancestry’s Role in Colorectal Cancer Risk: Brazilian Study Reveals Genetic Insights

by Dr. Michael Lee – Health Editor September 4, 2025

written by Dr. Michael Lee – Health Editor

Summary of the Research on Colorectal Cancer Risk in brazil

This research study, conducted with a large adn diverse Brazilian cohort (nearly 2,000 participants), has identified key genetic markers and the role of ancestry in colorectal cancer risk. Here’s a breakdown of the key findings:

1. Four Independent Genetic Markers:

The study identified four genetic markers that independently contribute to either increased risk or protection against colorectal cancer.
Importantly, these are not mutations occurring within the tumor itself, but rather normal genetic variations inherited from parents – like those influencing skin color. We are born with these variations.

2. Role of Ancestry:

Individuals with lower proportions of African and Asian ancestry were found to be at higher risk of developing colorectal cancer.
This supports the idea that genetic components inherited from African and Asian populations can have a protective effect. The researchers acknowledge this association could be linked to lifestyle factors common within these ancestral groups (e.g., diet rich in vegetables and fish).3. Importance of Sample Size & Diversity:

This study is significant due to its large sample size and representativeness of the Brazilian population, addressing limitations of previous smaller studies.
It highlights the importance of studying genetic diversity within specific populations, as findings from US or European studies may not directly apply to Brazil.

4. Future Implications: Personalized Medicine:

while these genetic variations cannot be changed,understanding them can lead to personalized prevention and tracking strategies. Individuals with risk-associated variants,combined with unhealthy lifestyles,face a considerably higher overall risk.
The researchers aim to combine genetic data with environmental factors to create more effective, tailored screening programs – prioritizing those with higher genetic risk.

5. Ongoing Research:

The team is now working on mapping up to 3 million genetic variations specifically within the Brazilian population.
The goal is to develop a unique risk score for Brazilians, taking into account thier specific genetic characteristics, to improve disease prevention and treatment.

In essence, this research emphasizes the importance of considering genetic ancestry and individual genetic profiles when addressing colorectal cancer risk in Brazil, paving the way for more effective and personalized healthcare strategies.

September 4, 2025 0 comments

Health

Childhood Skin Condition Linked to Obesity, Anxiety & Depression

by Dr. Michael Lee – Health Editor June 18, 2025

written by Dr. Michael Lee – Health Editor

Pediatric Hidradenitis Suppurativa: Study Links skin Condition to Obesity, Depression

Table of Contents

Pediatric Hidradenitis Suppurativa: Study Links skin Condition to Obesity, Depression

A comprehensive analysis of over 17,000 pediatric patients reveals a strong association between hidradenitis suppurativa (HS), a chronic inflammatory skin condition, and several comorbidities, including obesity, depression, and anxiety.The study, published in JAMA Dermatology, underscores the need for early detection and comprehensive clinical guidelines for managing HS in children and adolescents.

Comorbidities Linked to Pediatric HS

Hidradenitis suppurativa, sometimes referred to as inverse acne, is a long-term skin condition characterized by painful lumps under the skin, ofen in areas were skin rubs together, such as the armpits, groin, and buttocks. These lumps can heal slowly, reappear, and lead to tunnels and scarring. A significant challenge in pediatric HS is its impact on development during late childhood and adolescence, compounded by pain, frequent pus formation, and odor.

The research highlights that pediatric HS is frequently associated with other chronic health issues. For example,obesity,hyperlipidemia,and anxiety can affect nearly 93% of young patients with HS. Furthermore, studies suggest a link between HS and gut microbiome dysregulation, perhaps influencing mental health through the gut-brain axis.

Did You Know? The prevalence of obesity among children and adolescents in the United States was 19.7% between 2017-March 2020, according to the CDC. CDC

Study Details and Findings

The systematic review and meta-analysis included 19 observational studies encompassing 17,267 pediatric patients with HS and 8,259,944 controls. The average age of participants ranged from 12 to 17 years, with a majority being female (76.7%).

Obesity emerged as a highly prevalent comorbidity, affecting between 6% and 59% (combined proportion: 37%) of pediatric HS patients. While one study noted racial differences in obesity prevalence, the overall conclusion pointed to a significant association between HS and increased obesity risk in this population.

All studies indicated a higher incidence or prevalence of depression among HS patients compared to control groups, suggesting a probable link between HS and depression in pediatric patients. Anxiety (ranging from 1.4% to 33.6%) and depression (ranging from 2.7% to 13.7%) were the most commonly observed psychiatric comorbidities. Acne vulgaris was the most frequent dermatological condition in this patient group (combined proportion: 43%).

Pro Tip: Early intervention and mental health support are crucial for pediatric HS patients due to the high prevalence of anxiety and depression.

Implications for Treatment and Management

Currently, there are no specific treatment guidelines for pediatric HS, and management strategies are largely based on adult protocols.The study authors emphasize the importance of early detection of obesity, diabetes, mental health issues, and Down syndrome in affected children. They advocate for comprehensive clinical guidelines and multidisciplinary teams to address the complex needs of this patient population.

The researchers suggest the need for an early detection of obesity, diabetes, mental health problems and Down syndrome in those affected patients. “our findings highlight the need for comprehensive clinical guidelines for the detection of comorbidity in this population and emphasize the participation of multidisciplinary teams to achieve it,” the authors of the study concluded.

Key Comorbidities in Pediatric HS Patients

comorbidity	Prevalence Range	Combined Proportion
Obesity	6% – 59%	37%
Depression	2.7% – 13.7%	N/A
Anxiety	1.4% – 33.6%	N/A
Acne Vulgaris	N/A	43%

What are the long-term effects of HS on children’s mental health?

How can parents and caregivers best support children with HS?

Understanding Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by recurrent boil-like lumps, abscesses, and scarring, primarily affecting areas with apocrine sweat glands, such as the armpits, groin, buttocks, and breasts. The exact cause of HS is unknown, but it is believed to involve a combination of genetic, hormonal, and environmental factors.HS is not contagious and is not caused by poor hygiene.

The condition typically begins after puberty and can substantially impact a person’s quality of life due to pain, discomfort, and social stigma. While there is no cure for HS, various treatments can help manage symptoms and prevent disease progression.These include topical and oral medications, antibiotics, biologics, and surgical procedures.

Frequently Asked Questions About Pediatric Hidradenitis Suppurativa

Disclaimer: This article provides general data and should not be considered medical advice. Consult with a qualified healthcare professional for diagnosis and treatment of any medical condition.

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June 18, 2025 0 comments