Immunity⁢ Declines as Winter ⁢Approaches: Experts Urge⁤ Preventive‌ Healthcare

Gwangju, ‌Gyeonggi-do ⁢- As temperatures drop ⁢and air becomes drier,‌ a decline in⁢ teh body’s natural defenses is raising concerns about increased susceptibility to colds and bronchitis. Medical professionals ⁣are ⁢increasingly emphasizing preventive measures‍ to bolster immunity before the peak of winter ​illness ⁤season.

The shift towards proactive immunity strengthening includes treatments like high-dose vitamin injections, fluid therapy, and antioxidant infusions. These⁤ interventions aim to combat fatigue ⁤and enhance ‍metabolic function ‌by leveraging⁣ the roles of key nutrients. Vitamins C and D‍ are crucial for immune cell activity and antioxidant processes, while minerals⁢ like magnesium and selenium help mitigate cell damage. These treatments are intended to supplement, not replace, foundational health practices.

“Early ⁤winter presents a period where our bodies are more vulnerable due ⁢to environmental factors and a tendency for fatigue to accumulate,” explains⁤ Jeon Ji-hye, CEO of The ‍Wise healthcare Clinic.”Prioritizing sufficient sleep, a nutritious diet, ⁣and regular health‍ checkups is vital to assess and maintain immune status before illness takes hold.”

Experts recommend addressing chronic fatigue proactively, viewing it not simply as overwork but as a⁢ potential indicator⁢ of underlying immune ‍compromise.November‍ is highlighted as a notably opportune time for immunity management, ⁣combining healthy lifestyle choices with preventative medical care to maintain vitality throughout⁤ the winter months.

Kim Mi-kyung, a reporter for Medical Today, contributed to this report.

Winter Skin: Why Does It Darken, and How⁣ Can You Brighten It?

Winter’s arrival often brings more than just cozy sweaters⁢ and⁤ holiday ‍cheer; it can also bring changes to your skin. Many people notice their skin appearing darker during the colder months, a phenomenon that often leaves them ⁤puzzled. But the reasons behind this ⁢winter skin darkening are surprisingly complex and involve more than just ⁣a lack of sunshine.

The Science Behind Winter Skin Darkening

Reduced sun exposure is ⁣a key ⁣factor. Sunlight triggers melanin production, the pigment responsible for skin color. Less sunlight means less melanin, which might⁣ seem counterintuitive to darker skin. However,the process is ⁤more⁣ nuanced. The skin’s natural shedding⁣ process also accelerates in winter. This‌ increased shedding can lead to a buildup of dead skin cells on the surface, giving ⁤the skin a duller, sometimes darker appearance. [[1]] This is further complex by the fact that while the UV index is ​lower in⁢ winter, the sun’s rays can still penetrate deeply, causing pigmentation issues like spots and freckles. [[2]]

Furthermore, overzealous‍ exfoliation in an attempt to combat this dullness can backfire.”Overexfoliating in an attempt to remove dead skin cells can ‌also exacerbate the problem by triggering extra melanin production,” experts warn. [[3]] This highlights the importance of a balanced approach​ to winter skincare.

Strategies ⁢for Brighter Winter Skin

Maintaining adequate ​hydration is crucial. Switching to a richer moisturizer, such as⁤ one containing shea butter or cocoa butter, can‌ definitely help combat⁢ winter dryness and improve skin texture. [[3]] ‍ Remember, even ⁤on cloudy days, sunscreen is essential to protect against ⁢harmful UV rays that contribute to pigmentation. A⁤ gentle exfoliation routine, performed‌ less ⁣frequently than in warmer months, can help ​remove dead skin cells without overstimulating ‍melanin production.

For more persistent ⁣hyperpigmentation, ⁢consulting a dermatologist is recommended. They can ⁣assess your specific skin condition and recommend ‌appropriate treatments, which may include professional exfoliation, targeted skincare products, or even laser treatments.

By⁣ understanding the science behind winter skin darkening⁤ and adopting a‍ proactive skincare ​routine, you can maintain a brighter, healthier complexion throughout the colder months.

Understanding the Image: A ⁤Visual Analysis

The provided image, sourced from a​ korean medical news site, presents a⁢ visual​ challenge. Without accompanying text or context from ⁤the original⁤ article, a definitive interpretation is unfeasible. However, we can analyze the visual elements to offer potential interpretations and speculate on its intended ⁤meaning.

The image appears to be a banner or advertisement. Its design suggests a focus on health and wellness, possibly related to a ⁢specific medical procedure, product, or campaign. The color ⁣palette and overall aesthetic are clean and professional, suggesting a credible⁣ source. The lack of‍ readily identifiable text makes it​ difficult to pinpoint‍ the exact message, but the visual style points towards a sophisticated and trustworthy presentation.

Speculative Interpretations

Given the source’s association with a medical news site, several possibilities exist. The image could be promoting a new treatment, highlighting ⁣a accomplished​ medical breakthrough, or advertising a health-related product or service. The absence of English text limits ⁤our ⁤ability to definitively state its purpose, but the visual cues‍ strongly ⁢suggest a connection to the healthcare industry.

In the context of a U.S. audience, ‍the image’s ‍ambiguity could​ be leveraged ​to create intrigue. A marketing campaign could use a similar visual‍ style to‍ convey a sense of professionalism and trust, leaving ‍the specific details to be revealed through accompanying text or a website⁤ landing page.The clean design and lack of clutter would be appealing to a modern audience accustomed to visually-driven content.

Conclusion

While a precise interpretation of the image⁢ is impossible without further information, its​ visual​ elements suggest⁣ a connection to the medical field and⁢ a focus on professionalism and credibility. Its ambiguous nature could be strategically ​employed in marketing or advertising campaigns targeting a U.S. audience seeking‌ reliable health ⁢information.

Further investigation into the original source and accompanying text would be necessary to provide a more definitive analysis.

[메디컬투데이=이재혁 기자] Everyone wants to take care of their appearance to leave a good impression on others or to satisfy themselves. Accordingly, in addition to exercising such as gym or yoga, they also get help from functional cosmetics, and they also consider plastic surgery to get more immediate results.

However, for modern people who have difficulty finding time due to busy work, even finding time to go to the hospital is a task. In addition, surgery involving anesthesia and incisions can be somewhat burdensome. People with these concerns may consider dermatological procedures such as petite plastic surgery. Filler, one of the representative petit plastic surgery procedures, is a procedure that improves skin elasticity and volume by injecting hyaluronic acid.

First, if your skin appears hollow, you can expect natural and immediate volume improvement through filler. It can improve nasolabial folds and temple depressions, as well as dark circles that appear due to sunken under-eye areas.

Fine wrinkles can be improved by injecting filler into the shallow layer of the skin, such as the dermis layer, to make the skin more elastic. In addition, the effect of replenishing moisture in the skin can be expected through the moisture-attracting properties of hyaluronic acid. In addition, the overall three-dimensional appearance of the face can be enhanced through procedures on the nose, lips, forehead, and chin.

Fillers that can be applied to a variety of areas like this require a shorter treatment time than general plastic surgery and have a faster recovery, making the procedure relatively less burdensome. The fact that it is semi-permanent and that corrections can be made by injecting ingredients that dissolve the filler after the procedure also reduces the burden.

However, since filler is a dermatological procedure, it cannot be completely free from unexpected side effects such as delayed inflammatory reactions.

To prevent side effects, it is best to choose a filler whose safety has been guaranteed through multiple studies and a long clinical period. However, since it is often difficult for patients to find this on their own, it may be helpful to find a medical staff with extensive experience in performing the procedure for a long time.

In particular, medical staff who have seen more patients have more accumulated cases, have experienced more reactions and have treated them, and thus have a higher possibility of preventing them.

Director Ryu Jong-man of The Oline Clinic’s Gangneung branch said, “Before the procedure, it is best to make a treatment plan that takes into account each individual’s skin condition and condition through thorough medical treatment and receive guidance on the appropriate cycle.” He added, “If there is severe pain or redness in the treatment area, “If pustules occur, you must contact the hospital without delay and visit the hospital,” he emphasized.

If you have completed the procedure, you should refrain from strenuous exercise or drinking for 2 to 3 days after the procedure and be careful to prevent the treatment area from becoming infected. Additionally, it is best to avoid putting pressure on the treatment area as much as possible during the two weeks to one month while the filler settles.

Medical Today Reporter Jaehyuk Lee (dlwogur93@mdtoday.co.kr)

[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]

Considering the ⁣potential for ​both positive and negative outcomes, what advice would you give to someone contemplating their first filler injection treatment?

## The Rise of “Petit Plastic Surgery”: A Discussion‍ with ​Experts

**Introduction:**

Welcome ​to World-Today-News. Today, we’re diving into the trending world of‍ “Petit‌ Plastic Surgery,” ​focusing ‍on procedures like ⁤filler injections.⁣ Joining us are two esteemed guests: Dr. [Guest 1 Name],​ a ​dermatologist specializing in aesthetic procedures, and Ms. [Guest 2 Name], a beauty blogger‍ and⁢ advocate for informed skincare⁢ choices.

**Section 1: Understanding Filler Injections**

* **Question 1 (Dr. [Guest 1 Name]):** Dr.⁤ [Guest 1 Name], the article mentions that fillers are becoming increasingly popular, especially among individuals with busy lifestyles. What do‌ you think are the primary reasons behind this trend?

* **Question 2 (Ms. [Guest 2 Name]):** Ms. ⁢ [Guest 2 Name],⁣ you’ve researched⁤ diverse skincare⁣ options ⁤extensively. From your perspective, what ‌makes fillers appealing⁤ compared to alternative methods like topical creams ​or traditional plastic surgery?

**Section 2: Benefits‍ and Limitations‌ of Fillers**

* **Question 3 (Dr. [Guest 1 Name]):** Dr. [Guest 1 Name], the article highlights⁢ the versatility of fillers, mentioning their ⁣application in various areas like nasolabial folds, ⁣temples, ‌and lips. Can you elaborate on the specific benefits fillers offer in each of these areas?

* **Question 4 (Both Guests):** While the article emphasizes the benefits of ⁣fillers, it also acknowledges ‍potential side effects. What are some⁣ of ⁢the most important considerations individuals should be aware of before opting‍ for filler injections?

**Section 3: Safety and Expertise: Choosing⁤ the Right Provider**

* **Question 5 ⁣(Dr. [Guest 1 Name]):** While fillers are considered ⁢relatively safe, the⁣ article stresses the importance of selecting a skilled medical⁢ practitioner. What qualifications and‌ experience should people ‍look for when choosing a provider for filler injections?

* **Question 6 ‍(Ms. [Guest 2 Name]):** Ms. [Guest 2 Name], how can individuals effectively⁤ research and⁣ evaluate potential providers ⁢and ensure they are making a safe and informed decision?

**Section 4: Future Trends and Conclusion**

* **Question 7 (Both Guests):** Looking ahead, what future advancements⁤ or ‍trends do you foresee in the world of “Petit Plastic Surgery” and filler injections?

* **Closing Remarks:**

Thank​ you‌ to both Dr. [Guest 1 Name] and Ms. [Guest 2 Name] for sharing your invaluable expertise. ‍This discussion has ​shed light on⁣ the growing field of filler injections, ⁤highlighting⁣ both the ‍potential benefits and the importance of careful consideration and informed decision-making.

▲ Research results have shown that the onset of Alzheimer’s disease can be predicted early through a simple test. (Photo = DB)

[메디컬투데이=한지혁 기자] Research results have shown that the onset of Alzheimer’s disease can be predicted early through a simple test.

Research results showing that substances present in cerebrospinal fluid and blood can be used as biomarkers for early diagnosis of Alzheimer’s disease were published in the academic journal ‘New England Journal of Medicine (NEJM).’

According to World Health Organization (WHO) statistics, approximately 55 million people worldwide have been diagnosed with dementia, and the number is rapidly increasing.

Accumulation of abnormal proteins in the brain is observed in more than 60% of Alzheimer’s dementia patients, and many experts explain that these proteins appear to interfere with the function of nerve cells in the brain, causing the characteristic cognitive symptoms of dementia.

Most of the existing treatments for Alzheimer’s disease help manage symptoms, but do not stop the progression of dementia. Therefore, early diagnosis of Alzheimer’s disease and timely intervention are the most essential parts of the treatment of Alzheimer’s disease.

Recently, a Chinese research team observed changes in biomarkers in Alzheimer’s disease patients and more than 1,200 normal participants over 20 years and reported the results.

Researchers recruited participants aged 45 to 65 between January and June 2000, excluding those with cognitive impairment, family history of Alzheimer’s disease, hearing or vision impairment, and severe underlying medical conditions at the start of the study. done.

Participants underwent follow-up examinations every two to three years until 2020, which included the patients’ overall health status, cerebrospinal fluid and blood test data, and neuroimaging tests. Ultimately, the researchers matched 648 participants diagnosed with Alzheimer’s disease one-to-one with 648 participants without, based on demographic criteria, and compared the data from the two groups.

As a result, biomarkers such as ‘beta amyloid-42’, ‘beta amyloid-40’, ‘phosphorylated tau 181’, and ‘total tau concentration’ showed a statistically significant correlation.

A key finding of the study was that the participants’ levels of beta-amyloid-42 began to decline 18 years before they were diagnosed with Alzheimer’s disease. The ratio of beta-amyloid-42 and beta-amyloid-30 in cerebrospinal fluid has changed since 14 years ago. Phosphorylated tau 181 began to change 11 years before diagnosis, and total tau was also observed to increase 10 years before diagnosis.

In addition, the level of ‘neural filament (NfL)’ also increased 9 years before diagnosis, which appears to reflect damage and degeneration of nerve axons due to Alzheimer’s disease. It was confirmed that the decline in the volume of the hippocampus, the part of the brain responsible for memory, began eight years before diagnosis.

The researchers argued that time factors must be considered in changes in biomarkers related to Alzheimer’s disease, and that the findings of this study should be appropriately integrated into clinical diagnosis and treatment processes.

Medical Today Reporter Han Ji-hyuk (hanjh3438@mdtoday.co.kr)

[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]

2024-03-01 04:02:02

#pave #early #diagnosis #Alzheimers #Discovery #biomarkers #cerebrospinal #fluid #blood

▲ Research results have shown that a drug that reduces inflammation in the brain was developed using siRNA. (Photo = DB)

[메디컬투데이=조민규 기자] Research results have shown that a drug that reduces inflammation in the brain was developed using siRNA (small interfering RNA).

The research results were published in ‘Advanced Materials’ along with a discussion of the new delivery mechanism for delivering siRNA to microglial cells.

It is known that siRNA is involved in the process of translating mRNA into protein and can stop protein production. This means that inflammation in the brain can be lowered by stopping the translation of specific proteins. However, drugs that act on the brain have the limitation of being difficult to transport to the brain because they must pass through the blood-brain barrier.

Previous research has shown that inflammation is the main cause of many neurodegenerative diseases, including Alzheimer’s disease. In particular, a transcription factor called PU.1 was found to be related to neuroinflammation that occurs in Alzheimer’s disease.

MIT researchers, who showed that inflammation can be reduced by suppressing the PU.1 transcription factor, confirmed that siRNA delivered to microglial cells can reduce the expression of the PU.1 transcription factor.

Author Dr. Owen Fenton noted that prolonged neuroinflammatory conditions lead to long-term damage to brain cells, and reducing this early on can improve the chances of recovery.

Additionally, the researchers developed seven lipid nanoparticle (LNP) formulations to transport siRNA. The LNP formulation has already been used in Pfizer’s COVID-19 vaccine and is known to have confirmed safety and efficacy.

Through experiments on rats, researchers confirmed that injection into cerebrospinal fluid was most effective.

Medical Today Reporter Jo Min-gyu (awe0906@mdtoday.co.kr)

[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]

2023-12-21 23:09:46

#siRNA #delivery #LNP #preparation #reduces #neuroinflammation

▲ Research results have shown that OvaPrint, a new blood test, detects early-stage ovarian cancer with 91% accuracy. (Photo = DB)

[메디컬투데이=최재백 기자] The blood test OvaPrint has been shown to detect early-stage ovarian cancer with over 90% accuracy.

Research results showing that OvaPrint, a new blood test, detected early-stage ovarian cancer with 91% accuracy were published in the academic journal ‘Clinical Cancer Research’.

According to 2020 data, ovarian cancer is the third most common gynecological cancer worldwide. The most common type of ovarian cancer, high-grade serous ovarian cancer (75%), has an estimated 10-year survival rate of approximately 55% if detected early. However, there is currently no reliable screening test for ovarian cancer, so it is usually detected at an advanced stage and the 10-year survival rate is only 15%.

The early symptoms of ovarian cancer, such as abdominal distension, abdominal pain, and frequent urination, are common during normal menstrual cycles, urinary tract infections, or irritable bowel syndrome, so ovarian cancer is often diagnosed as another disease until symptoms worsen. Additionally, anatomically, the ovaries are located deep in the abdominal cavity, making it difficult to detect tumors during a pelvic examination.

Accordingly, a research team at the Keck School of Medicine of the University of Southern California is developing a new blood test to diagnose ovarian cancer in the early stages, and is currently able to determine whether a pelvic mass is malignant or benign with an accuracy of 91%. It was reported that they succeeded in distinguishing.

OvaPrint, developed by the research team, helps diagnose various types of early ovarian cancer, including the most common and fatal high-grade serous ovarian cancer, and determines whether a pelvic mass is malignant.

OvaPrint uses cell-free DNA methylation liquid biopsies to detect cell-free DNA, small pieces of DNA shed from tumor cells into the blood. Methylation is a complex reaction that regulates DNA in cells and is often used as a diagnostic biomarker because it can change gene expression in the body.

OvaPrint detects DNA methylated by specific nucleic acids in cell-free DNA.

The research team evaluated OvaPrint on 370 tissue and blood samples from early-stage ovarian cancer, benign pelvic tumors, and normal ovaries, and reported that OvaPrint distinguished between ovarian cancer and benign pelvic tumors with 91% accuracy.

Furthermore, they are planning a follow-up study targeting hundreds of patients, and if the efficacy of OvaPrint is proven in the subsequent study results, they plan to release it for clinical use within two years.

Experts praised OvaPrint’s accuracy, saying the technology to identify cell-free DNA originating from malignant tumors makes the test more sensitive than traditional tumor markers such as CA125.

Meanwhile, given that it is still early research data, additional clinical trials and high-quality observational data from a large sample group are needed to prove the efficacy and safety of OvaPrint, he added.

Medical Today Reporter Jaebaek Choi (jaebaekchoi@naver.com)

[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]

2023-10-18 07:24:49

#OvaPrint #blood #test #detect #early #ovarian #cancer #initial #experimental #accuracy