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Factors Influencing Maternal and Neonatal Outcomes in Hypertensive Disorders of Pregnancy
Hypertensive disorders in pregnancy pose significant risks to both mothers and newborns. This study investigated factors associated with adverse outcomes in women admitted to Princess Christian Maternity Hospital in Freetown, Sierra Leone, seeking to identify key areas for improved clinical management.
Our analysis revealed that gestational age at admission and the length of hospital stay were consistently linked to both maternal and neonatal outcomes. These findings emphasize the critical importance of early identification and effective intervention for hypertensive disorders before they progress to more severe stages. Prolonged hospitalizations – exceeding seven days – were also considerably associated with poorer outcomes, likely reflecting the presence of more complex cases requiring extended monitoring and care. Interestingly, diastolic blood pressure measured upon admission was specifically associated with neonatal health. This highlights the potential benefit of prioritizing regular diastolic blood pressure checks during prenatal care,as early detection allows for timely interventions and enhanced fetal surveillance,perhaps minimizing risks to the baby [1,30].
While pharmacological interventions like antihypertensive medications and magnesium sulfate are standard treatments, our study did not find a statistically significant direct association between their use and improved outcomes. this suggests that medication alone may not be enough. A more holistic approach is needed, encompassing proactive risk assessment, community-based screening programs, thorough patient education, and robust referral systems to ensure women receive appropriate care throughout their pregnancy. The advancement and implementation of predictive models, incorporating factors like maternal history and relevant biomarkers, as proposed by O’Gorman Neil and colleagues [32], could further refine early detection and personalize treatment strategies.
Study limitations
it’s important to acknowledge the limitations of this research. As a retrospective study, it is susceptible to inherent biases, including selection bias and potential inaccuracies in recalling past events. Moreover, the findings are based on data collected from a single hospital in a specific geographic location (Freetown, Sierra Leone). Therefore, generalizing these results to other healthcare settings or populations should be done with caution. the cross-sectional design of the study prevents us from establishing definitive cause-and-effect relationships.
References
[1] [Original Reference 2 details]
[30] [Original Reference 30 details]
[31] [Original Reference 31 details]
[32] [Original Reference 32 details]
Key Changes & Considerations:
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Tone: I’ve aimed for a slightly more accessible tone while maintaining the scientific rigor.
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