Chyler Leigh, a former co-star of Eric Dane on the long-running medical drama Grey’s Anatomy, publicly mourned his death on Saturday, February 21st, describing the loss as “devastating.” Dane, 53, died on February 19th following a battle with amyotrophic lateral sclerosis (ALS).
“The last 48 hours have been devastating,” Leigh told E! News. “I never thought I would be using the term ‘had or was,’ but here we are. And I hate it.”
Leigh, who portrayed Lexie Grey, the on-screen love interest of Dane’s character, Mark Sloan (known as “McSteamy”), remembered Dane as a man with “a heart of gold.” She highlighted his infectious humor and his ability to engage in deep philosophical conversations, even although on set. “His humor and, especially, his laugh was infectious,” she said.
Beyond his professional life, Leigh emphasized Dane’s devotion to his family. “He was an amazing father and loved his girls FIERCELY,” she stated, referring to his daughters, Billie, 15, and Georgia, 14.
Dane revealed his diagnosis of ALS in April 2025. His family confirmed his death in a statement, noting he spent his final days surrounded by his wife, Rebecca Gayheart, and their daughters. Although separated, Gayheart had withdrawn her 2018 divorce filing in March 2025.
Both Leigh and Dane’s characters were involved in a pivotal plane crash storyline during Grey’s Anatomy. Leigh’s character, Lexie Grey, was killed off in the Season 8 finale. While Dane’s character, Mark Sloan, initially survived the crash, he died in the Season 9 premiere.
The family’s statement similarly highlighted Dane’s commitment to raising awareness and funding research for ALS during his illness. “Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight,” the statement read. The family has requested privacy during this time.