Keto Diet shows Promise as Adjunctive Therapy for Depression, New Study Finds
A new study from Ohio State University (OSU) indicates the ketogenic diet may offer benefits for individuals struggling with depression. Researchers found significant improvements in mood among participants following a keto eating plan-less than 50 grams of carbohydrates per day, combined with higher fat and moderate protein-prior to the study.
The research team provided “extensive education” to participants, emphasizing eating when hungry and stopping when full, without calorie tracking. “it was very crucial to make sure participants knew what they were getting themselves into,” explained Drew Decker, a graduate student and the study’s first author. The individualized approach focused on tailoring dietary suggestions based on participants’ food preferences to encourage adherence.
While the study lacked a non-keto control group, researchers were surprised by the “magnitude of improvements” observed. Jeff Volek, a human sciences professor at OSU and lead author, noted, “There’s a lot of evidence that ketones improve brain function and can change people’s mood through a variety of different neurochemicals.” He suggested ketones may directly impact neurotransmitters related to depression and possess anti-inflammatory properties that could contribute to mood enhancement.
Participants in the study experienced an average weight loss of 11 pounds and a 2.4% decrease in body fat, with all but one individual losing weight. Volek highlighted a potential connection between weight and mental health, noting that individuals who are overweight or obese are more likely to experience depression.
Volek recommends considering option eating patterns for those with mental health disorders, stating, “If you are someone who is suffering from a mental health condition, this is another tool in the toolbox that might be worth trying.” He advises seeking guidance from a professional informed in the ketogenic diet for support.