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Aโ new study published in Nature โคMedicine has revealed distinct immune responses triggered by vegan and ketogenic diets in humans, potentially offering insights intoโ personalized nutritionโ strategies. The research, led โขby V.M. โLink and colleagues, details how these dietary approaches โขdifferentially impact โฃperipheral immune signatures.
The investigation, detailed in the article “Differential peripheral immune signatures elicited โขby vegan versus ketogenic diets in humans,” foundโข that veganโ diets were associatedโค with specific immune profiles, while ketogenic diets elicitedโ different,โ equally distinct responses. Researchers analyzed immune cell populations and โcytokineโ levels โin participants following each diet.
The study highlights the complexโ interplay between diet and the immune system. The findings, published in 2024 โข(30:560-572), could have implications for managing โขinflammatory conditions and optimizing immune functionโ through dietaryโ interventions. Further research is needed to fullyโค elucidate the mechanisms underlying these observed differences and to determine the long-term health consequences of these dietary-induced immune shifts.
Related commentaryโค responding to work by D.S.โข ludwig et al. was publishedโฃ in The Americanโฃ Journal ofโ Clinical Nutrition in 2025 (121), authored by K.D. Hall, C.M. Sciarrillo, J.Guo, A. Hengist, and V.L. Darcey. This response provides additional context to the ongoing discussion surrounding dietary approaches and metabolic health.
The studyโค isโค accessible through PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=38291301) and PubMed Central (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10878979), and alsoโฃ through โคCAS (https://www.nature.com/articles/cas-redirect/1:CAS:528:DC%2BB2cXisVyqsr8%3D) and Google Scholar (http://scholar.google.com/scholar_lookup?&title=Differential%20peripheral%20immune%20signatures%20elicited%20by%20vegan%20versus%20ketogenic%20diets%20in%20humans&journal=Nat.%20Med.&volume=30&pages=560-572&publication_year=2024&author=Link%2CVM).
The ludwig et al. work referenced in the commentaryโ is also available viaโค Google Scholar (
