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Parkinson’s Disease: Symptoms, Causes, and Treatment

This article discusses Parkinson’s disease, it’s causes, symptoms, adn management. Here’s a breakdown of the key facts:

What is Parkinson’s Disease?

Parkinson’s disease is a neurodegenerative disorder caused by the destruction of dopamine-producing nerve cells in the brain.

Causes of Dopamine Neuronal Reduction:

Environmental pollution
Toxic substances (insecticides, herbicides)
genetic factors
Aging (especially after 60)
Mitochondrial dysfunction
Accumulation of unnecessary proteins

Symptoms of Parkinson’s Disease:

Motor Symptoms (appear when 60-80% of dopamine neurons are lost):
Trembling (hands, legs, jaw, tongue, lips) – present in about 70% of patients initially.
Slower movements (bradykinesia) – making tasks like buttoning clothes, writing, brushing teeth, and eating difficult.
Muscle stiffness (rigidity).
Unstable posture and difficulty with balance.
“Freezing” – sudden inability to move while walking.
Difficulty initiating movement, changing direction, or navigating obstacles.
Non-Motor Symptoms:
cognitive disorders.
Neuropsychiatric symptoms: depression,anxiety,fatigue,hallucinations,delusions,impulse control disorders. Sleep disorders: insomnia, low sleep quality, sleep seizures, restless legs syndrome, REM sleep behavioral disorder. Loss of smell (olfactory dysfunction): This can occur up to 10 years before other symptoms appear.Diagnosis and Progression:

If you suspect Parkinson’s, seek medical attention promptly.
While there’s no cure, treatments like levodopa can be effective in the early stages (2-3 years).
After 3-5 years, complications can arise, leading to involuntary movements.Complications and Risks:

Parkinson’s itself isn’t fatal, but its complications are hazardous. Falls and bone fractures due to postural instability.
Pneumonia (aspiration pneumonia) due to difficulty swallowing (dysphagia),which affects over 80% of patients. This is the most common cause of death in Parkinson’s patients.
Reduced quality of life due to these complications.

Medications to Avoid:

Certain digestive agents (e.g., McSorong, Levopride).
Certain stabilizers (e.g., haloperidol, perfenajin).

Management and Treatment:

Medication: Drug therapy is a cornerstone of treatment.
Exercise: Crucial for management.Recommended exercises include:
Walking
Stretching
Strength training (resistance training)
Swimming
Gymnastics
Tai Chi
Yoga
Indoor cycling
Aquarobics
nutrition: balanced nutrition and regular eating habits are vrey crucial.the article highlights that Parkinson’s disease is a progressive neurological disorder with a range of motor and non-motor symptoms. While there’s no cure, early diagnosis, medication, and consistent exercise are vital for managing the condition and improving the quality of life for patients.

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