Lactate delivered directly into the bloodstream may mimic the cognitive benefits of exercise by prompting the release of a key hormone, according to research published September 23, 2025. The finding offers a potential pathway for individuals unable to engage in regular physical activity to experience similar mental enhancements.
The study, detailed in findings released today, reveals that intravenous lactate infusion stimulates the production of irisin-a hormone often dubbed the “exercise hormone”-wich is linked to improved brain function and mood. This discovery could have importent implications for those with mobility limitations, chronic illnesses, or age-related cognitive decline, potentially offering a pharmacological approach to boost brain health. Researchers retrieved the data on September 23, 2025, and published it via medicalxpress.com.
Scientists found that administering lactate intravenously triggered irisin release in study participants, replicating some of the neurological effects observed after a workout. While the precise mechanisms are still under investigation, the research suggests lactate acts as a signaling molecule, effectively “tricking” the body into believing it is indeed exercising.
The research team emphasizes that this is preliminary work and further investigation is needed to determine the long-term effects and optimal dosage of lactate infusions for cognitive enhancement. Future studies will focus on exploring the potential therapeutic applications of this finding and assessing its safety and efficacy in diverse populations.
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Lactate IV infusion found to trick the body into releasing a hormone behind that post-workout brain boost (2025,September 23)
retrieved 23 September 2025
from https://medicalxpress.com/news/2025-09-lactate-iv-infusion-body-hormone.html
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