FDA Warns of Severe itching After Stopping Certain Allergy Meds
The U.S. Food and Drug Administration (FDA) has issued a warning regarding the potential for severe itching after discontinuing long-term use of two common allergy medications: cetirizine (Zyrtec) and levocetirizine (Xyzal). This side affect, while rare, can significantly impact a patient’s quality of life.
The Warning in Detail
Earlier this month, the FDA alerted the public to the possibility of experiencing rare but severe itching
after stopping these medications. This reaction can occur with both prescription and over-the-counter versions. Consequently,the FDA is mandating that manufacturers and pharmacists include warnings on the product labels. The updated prescribing facts will also note that restarting the medication may alleviate the itchiness.
pruritus: The Medical Term for Itching
The FDA reported over 200 cases of this itching, also known as pruritus,in individuals who had been taking the medications daily for at least a few months,and frequently enough for years. Notably, these patients did not experience itching before starting the medications. In some instances,the itching was severe and widespread,necessitating medical intervention and significantly affecting the patient’s ability to function.
Affected Medications: Cetirizine and Levocetirizine
Cetirizine and levocetirizine are antihistamines that work by blocking histamine, a substance released by the body during allergic reactions. This blockage helps to relieve symptoms such as runny nose, sneezing, itchiness, and swelling. These medications are approved for treating both seasonal and year-round allergies, as well as chronic hives.
What to Do If You Experience Itchiness
The FDA advises that if you experience extreme itchiness after stopping long-term use of either prescription or over-the-counter cetirizine or levocetirizine, you should consult a healthcare professional. Reports of this adverse reaction were submitted through the FDA’s adverse Event Reporting System.
The FDA emphasizes the importance of discussing the benefits and risks of long-term use of these medications with your doctor, especially if you plan to take them for more than a few months. Individual responses to medication can vary based on factors such as health status, genetics, and other medications being taken. Thus, the FDA cannot predict whether everyone taking these drugs long-term will experience the same reaction.
