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Drought During Pregnancy Increases Risk of Premature Birth and Fetal Growth Alterations

August 26, 2026 Dr. Michael Lee – Health Editor Health

Prolonged exposure to drought conditions during pregnancy elevates the risk of preterm birth by up to 5%, with cumulative water scarcity compounding fetal growth restriction and maternal health vulnerabilities. According to an international study coordinated by the Institut de Recerca Sant Pau (IR Sant Pau) and published in The Lancet Regional Health – Americas, chronic environmental stress represents a possible determinant of maternal and child health.

  • Preterm Risk Rises: Continuous water scarcity elevates the baseline probability of premature delivery by 2%, scaling up to 5% during severe and extreme drought phases.
  • Fetal Growth Impacts: Prolonged droughts spanning six to nine months increase the likelihood of babies being born small for their gestational age by 1% to 2%.
  • Socioeconomic Disparities: In low-development municipalities, the probability of preterm birth spikes between 8% and 10% following prolonged exposure.

Epidemiological Scope and Research Methodology

The investigation analyzed nearly 30 million birth records in Brazil spanning from 2001 to 2020. Researchers linked data from the 100 Million Brazilian Cohort, maintained by the Center for Data and Knowledge Integration for Health (CIDACS), alongside the country’s Live Births Information System. Environmental metrics were sourced from the CIDACS-Clima platform, supported by the Wellcome Trust. The project itself received funding from the Gates Foundation through its Grand Challenges program, in collaboration with the Brazilian Ministry of Health (DECIT) and the National Council for Scientific and Technological Development (CNPq).

To quantify environmental stress, investigators utilized the Standardized Precipitation-Evapotranspiration Index (SPEI). This metric accounts for both rainfall deficits and temperature-driven water loss across three-, six-, and nine-month intervals preceding delivery. Lead investigator Dr. Aline Rocha, a researcher at the IR Sant Pau SalutData Lab, notes that the findings reframe climate phenomena as determinants. “Our results show that the drought is not solely an environmental or agricultural issue, but also a potential determinant of maternal and child health,” Dr. Rocha states.

Pathophysiological Mechanisms and Environmental Synergies

Clinical complications stem from an accumulation of physiological stressors. Dehydration, maternal heat stress, compromised nutritional intake, and restricted access to routine prenatal monitoring compound during dry spells. Furthermore, water scarcity frequently intersects with secondary environmental hazards such as wildfires, pollution, and inflation in food prices. Project scientific coordinator Dr. Otavio Ranzani highlights that these overlapping factors can considerably increase vulnerability during gestation. When drought conditions coincide with acute heatwaves, the risk of prematurity increases.

Dr. Otavio Ranzani i Dra. Aline Rocha
Photo: recercasantpau.cat

Socioeconomic Vulnerability and Global Implications

The data reveals a stark socioeconomic divide in clinical outcomes. Because the analyzed cohort captures populations registered for social assistance programs, the dataset highlights communities already facing food insecurity and infrastructure limitations. In regions with very low development indexes, prolonged drought exposure drove preterm birth rates up by 8% to 10%.

Drought During Pregnancy Increases Risk of Premature Birth and Fetal Growth Alterations
Photo: elperiodico.com

Although the registry data originates in Brazil, study authors emphasize that the conclusions are valid for other climate-vulnerable regions, including the Mediterranean basin and Spain.

Future Directions in Planetary Health

The research team at IR Sant Pau is expanding this epidemiological line of inquiry to evaluate whether cumulative drought exposure during pregnancy generates sequelae in child growth and development up to five years of age.

*Disclaimer: The information provided in this article is for educational and scientific communication purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider regarding any medical condition, diagnosis, or treatment plan.*

ECU Health warns extreme heat may increase risk of premature birth

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