Coffee consumption may significantly reduce the risk of dementia, including Alzheimer’s disease, according to research presented by Dr. Jimmy Mohamed on RTL radio on February 27, 2026. The findings stem from a Harvard University study tracking 130,000 individuals over 43 years.
The study revealed that drinking two to three cups of coffee daily, alongside one to two cups of tea, was associated with a nearly 20% reduction in dementia risk. Dr. Mohamed, speaking on RTL, stated, “Coffee is the best drink that exists. Period. Really.”
Researchers believe the protective effect is linked to caffeine’s interaction with adenosine A2A receptors in the brain. According to the Alzheimer’s Foundation, blocking these receptors modulates neuronal signals and reduces inflammation, potentially safeguarding brain cells. Further research, cited by Top Santé, indicates that caffeine may limit the production of beta-amyloid peptides and abnormally phosphorylated tau protein – both hallmarks of Alzheimer’s disease.
The mechanisms suggest caffeine doesn’t merely provide alertness but actively engages with brain receptors involved in inflammation and potentially mitigates processes linked to Alzheimer’s lesions. A LinkedIn post by Grégory Harmand highlighted the study, emphasizing the Harvard research and Dr. Mohamed’s endorsement.
While the study points to potential benefits, experts emphasize moderate consumption. The World Health Organization recommends limiting coffee intake to a maximum of four cups per day. The findings suggest that, when consumed in moderation, coffee could contribute to cognitive protection alongside its known effects on vigilance and concentration.
The research builds on existing studies exploring the benefits of caffeine and tea. Jimmy Mohamed’s presentation on RTL follows previous health-focused discussions, including a recent analysis of the potential protective effects of cheese against dementia, also presented on the program.