CDC Launches Rx Awareness Campaign to Combat Prescription Opioid Epidemic
The Centers for Disease Control and Prevention launched a targeted public communication initiative on September 25, 2017, designed to assist state health agencies in curbing the prescription opioid overdose epidemic. Titled Rx Awareness, the campaign features video, audio, and digital testimonials from individuals recovering from opioid use disorder and families who have lost relatives to overdoses. According to the U.S. Department of Health and Human Services, the campaign utilizes the tagline “It only takes a little to lose a lot” to educate the public on the dangers of prescription opioid use for both medical and non-medical purposes.
- The CDC launched the Rx Awareness campaign on September 25, 2017, deploying testimonials across four initial states to warn against prescription opioid misuse.
- Between 1999 and 2015, prescription opioid overdoses accounted for more than 183,000 deaths in the United States, according to federal figures.
- Federal data indicates that 12.5 million people misused prescription opioids in 2015, with approximately three out of four new heroin users reporting prior misuse of prescription opioids.
Epidemiological Scope and Federal Strategy
Department of Health and Human Services (HHS). Daily emergency department data shows that more than 1,000 people are treated for misusing prescription opioids, and more than 40 individuals die daily from prescription opioid overdoses. “The U.S. Department of Health and Human Services is committed to using evidence-based methods to communicate targeted messages about the opioid crisis and prevent addiction and misuse in every way we can,” said HHS Secretary Tom Price, M.D., noting that prevention forms a core component of the five-point strategy unveiled under the Trump Administration.
Among new heroin users, approximately three out of four report having misused prescription opioids prior to initiating heroin use.
State-Level Deployment and Multi-Week Rollout
The Rx Awareness campaign relies heavily on partnerships with state and local health agencies to distribute materials and share resources. Beginning September 25, 2017, campaign advertisements were slated to run for a 14-week duration in four initial states: Ohio, Kentucky, Massachusetts, and New Mexico. Broader releases are scheduled for additional states funded through CDC programs, specifically the Prescription Drug Overdose: Prevention for States and Data-Driven Prevention Initiative programs.
Campaign materials encompass video spots, audio advertisements, social media campaigns, internet banners, web graphics, billboards, and posters designed to highlight the risks of prescription opioids. “This campaign is part of CDC’s continued support for states on the frontlines of the opioid overdose epidemic,” said CDC Director Brenda Fitzgerald, M.D. “These heartbreaking stories of the devastation brought on by opioid abuse have the potential to open eyes – and save lives.”
Integration with Federal Health Priorities
The communication initiative aligns directly with broader federal efforts to manage pain and combat addiction. Rx Awareness and related CDC state overdose prevention programs operate under the HHS five-point strategy. This framework focuses on improving access to prevention, treatment, and recovery services—including the full range of medication-assisted treatments—while targeting the distribution of overdose-reversing drugs. Furthermore, the strategy supports cutting-edge research on pain and addiction, strengthens public health data reporting, and advances safer, more effective clinical practices for pain management.

For patients navigating chronic pain conditions or managing complex recovery trajectories, clinical guidance requires close coordination with qualified medical professionals. Individuals seeking specialized support for substance use disorders can consult with vetted addiction medicine specialists and treatment facilities through the network. Similarly, healthcare organizations and clinics managing compliance protocols around controlled substances can partner with services to ensure adherence to federal and state regulatory standards.
Disclaimer: The information provided in this article is for educational and scientific communication purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider regarding any medical condition, diagnosis, or treatment plan.