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B12 Deficiency & Gray Hair: What a Dermatologist Says

February 14, 2026 Dr. Michael Lee – Health Editor Health

Premature graying of hair may be directly linked to Vitamin B12 deficiency, according to Dr. Antonella Tosti, a professor of dermatology at the University of Miami. Dr. Tosti’s research indicates that hair follicles are particularly vulnerable to nutritional deficiencies, and a lack of B12, commonly found in oily fish like salmon, can accelerate the loss of pigmentation in hair.

“Hair follicles are extremely sensitive to nutritional deficiencies,” Dr. Tosti stated. “Vitamin B12 deficiency, found in oily fish such as salmon, is directly related to premature graying of hair. Regular consumption of these nutrients has been observed to extend the lifespan of melanocyte cells.”

The findings align with growing research into the connection between diet and hair health. Although stress is also recognized as a contributor to hair loss, as reported by The New York Times in 2023, Dr. Tosti’s work focuses specifically on the role of micronutrients in maintaining hair color.

The research suggests that adequate B12 intake may facilitate preserve the function of melanocytes, the cells responsible for producing melanin, the pigment that gives hair its color. The precise mechanisms by which B12 impacts melanocyte longevity are still under investigation.

Dermatology Times recently published an article examining the effectiveness of supplements in managing hair loss, indicating a broader interest in nutritional interventions for hair health. However, the extent to which supplementation can fully address B12 deficiency and reverse graying remains an area of ongoing study.

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