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AI Predicts Pancreatic Cancer Survival After Surgery | News

AI Predicts Pancreatic Cancer Survival wiht Unprecedented Accuracy,Boosting Post-Surgery Outcomes

Seoul,South Korea – June 30,2025 – A groundbreaking development utilizing artificial intelligence (AI) is poised to revolutionize the prognosis prediction for pancreatic cancer patients undergoing surgery,offering a beacon of hope for a disease notoriously known for its high recurrence rate and low survival rates. Researchers at Samsung Seoul Hospital have demonstrated a strong correlation between AI-analyzed spatial tumor infiltrating lymphocyte (TIL) density and patient survival rates.

For years, tumor infiltrating lymphocytes – immune cells within the tumor – have been recognized as a potential indicator of post-treatment prognosis. However, manual measurement of TIL density has been a importent barrier to widespread clinical adoption due to its time-consuming nature and susceptibility to observer variability.

Now, the team, led by Professor Joo-Kyung Park of Pancreatic Dam-Dam Division, along with Professors Han In-woong and jang Ki-taek, has overcome this hurdle by leveraging Lunit’s ‘Lunit Scope IO’, an AI-powered immune-based analysis platform.This technology accurately quantifies TILs within the tumor microenvironment, effectively differentiating between tumor and surrounding tissue.

A retrospective cohort analysis of 304 pancreatic cancer patients revealed striking results. Patients exhibiting an “immune-inflamed phenotype” – characterized by a high density of TILs – experienced a median survival period of 35.11 months,a staggering three times longer than those with an “immune-desert phenotype” (11.6 months). Moreover, patients with an immunosuric molding showed a progressive survival period of 14.63 months, double that of immune-deficient patients (6.57 months).

“This AI-driven approach allows for a more precise and efficient evaluation of TIL density and distribution in pancreatic cancer patients,” stated Professor Park. “The implications for personalized treatment strategies and improved patient outcomes are immense.”

This breakthrough promises to significantly impact the clinical management of pancreatic cancer, potentially leading to more informed treatment decisions and ultimately, increased survival rates for patients facing this devastating disease. Further research and wider implementation of this AI technology are anticipated in the coming months.

Keywords: Pancreatic Cancer, Artificial Intelligence, TILs, Prognosis, Survival Rate, Lunit, Samsung Seoul Hospital, Cancer Treatment, Immune Response, AI in Healthcare.

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