Endometrial Cancer: Dos and Don’ts for Treatment & Beyond

Navigating a new endometrial cancer diagnosis requires patients to be proactive and informed, according to gynecologic surgical oncologist Robert DeBernardo, MD, of Cleveland Clinic. While acknowledging each patient’s experience is unique, Dr. DeBernardo outlined key “dos and don’ts” for those undergoing treatment.

One of the most critical steps, Dr. DeBernardo emphasized, is to ask questions. “Cancer diagnosis and treatment involve a lot of minutia that can be hard to wrap your head around,” he said. “We’re here to facilitate you understand it and to walk you through it.” He suggested keeping a running list of questions for oncology appointments.

Equally crucial is paying attention to the body’s signals. Patients should promptly report any new or worsening symptoms, including vaginal bleeding, unusual discharge, changes in appetite, or unexplained weight loss, to their oncologist. Managing treatment side effects is also a priority, with access to a range of specialists available to provide support.

Maintaining overall health through lifestyle choices is also vital. Dr. DeBernardo recommends a balanced diet rich in protein, fruits and vegetables to support the immune system, along with adequate rest and hydration. Avoiding alcohol, smoking, and risky foods – such as leftovers or undercooked meats – is also advised, as cancer treatments can weaken the immune system.

Beyond the physical aspects, Dr. DeBernardo stressed the importance of mental health. He noted that a cancer diagnosis can evoke a range of emotions and encouraged patients to seek support from therapists specializing in cancer care or through support groups. “It’s a lot to digest and process, and it’s a lot to place your body through, so it’s important to have people in your life on that journey with you,” he stated.

Adhering to scheduled appointments is critical for monitoring progress and adjusting treatment plans. Dr. DeBernardo explained that endometrial cancer treatment often requires close follow-up.

Care doesn’t end with the completion of treatment. Follow-up appointments are essential for several years post-treatment, with the frequency decreasing over time. For the first two to three years, appointments are typically scheduled every three to six months, transitioning to every six months until the five-year mark, and then annually. Dr. DeBernardo also recommends maintaining a relationship with a gynecologist for ongoing concerns, even after the five-year follow-up period concludes. “It can be hard to find a provider out of the blue and be evaluated on short notice,” he said. “So, when you’ve had uterine cancer, it’s always important to maintain a relationship with a provider who you can talk to about gynecologic concerns and see in a pinch, if you demand to.”

Dr. DeBernardo is the section head of the Department of Gynecologic Oncology at Cleveland Clinic, director of the Peritoneal Surface Malignancy Program, and holds the Laura J. Fogarty Endowed Chair in Uterine Cancer Research. He is board-certified in obstetrics and gynecology, as well as gynecologic oncology.

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