Stockholm, Sweden – October 6, 2025 – The Nobel assembly at Karolinska Institutet has awarded the 2025 nobel Prize in Physiology or Medicine to three researchers recognizing their groundbreaking discoveries concerning the human immune system, specifically focusing on peripheral immune regulation. The award acknowledges decades of collaborative work that has fundamentally reshaped our understanding of how the body defends itself against disease and offers new avenues for treating autoimmune disorders and cancer.
This year’s prize highlights the critical importance of immune system research, particularly as global health faces emerging infectious diseases and a rising incidence of autoimmune conditions. The laureates’ work provides a foundational understanding for developing targeted immunotherapies, potentially revolutionizing treatment strategies for millions affected by immune-related illnesses. The Nobel Committee will formally confer the award at a ceremony in December.
The Nobel Prize was awarded for discoveries related to the mechanisms governing the peripheral nervous system’s control of immune responses. this research has illuminated how the body maintains immune homeostasis, preventing excessive inflammation and autoimmune reactions. Further details regarding the specific contributions of each laureate will be released by the Nobel Committee in the coming days.
The prize includes a cash award of 11 million Swedish krona (approximately $1.04 million USD as of October 6, 2025), which will be shared equally among the three scientists. The announcement was made at the Karolinska institutet in Stockholm at 10:32:14 CEST.
Citation: The Nobel Prize in medicine goes to 3 scientists for work on the human immune system (2025, October 6) retrieved 6 October 2025 from https://medicalxpress.com/news/2025-10-nobel-prize-medicine-scientists-peripheral.html
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