Blood Type A Linked to Increased Risk of Early Stroke, New Research Finds
PARIS – Individuals with blood type A may face a heightened risk of experiencing stroke at a younger age, according to a study published October 5, 2025, by Le Gaz. The research, which analyzed data from a large cohort across multiple countries, reveals a statistically significant correlation between blood type A and earlier onset of stroke.
While stroke is generally considered an age-related condition, this study suggests genetic predisposition plays a role, perhaps allowing for earlier and more targeted preventative measures. Researchers emphasize the need for further investigation to fully understand the underlying mechanisms driving this increased risk, but the findings offer a new avenue for personalized health risk assessment.
The study, conducted by researchers including Kittner, involved participants from North America, Europe, Japan, Pakistan, and australia. Even though the cohort included individuals from diverse backgrounds, 35% were of non-European origin, prompting calls for future research with a more representative sample to validate the results across different populations. “We clearly need more follow-up studies to clarify the mechanisms of increasing the risk of stroke,” Kittner stated.
The research builds upon existing knowledge linking the ABO locus – the part of the genome coding for blood type - to other cardiovascular issues. Previous studies have associated blood types A and B with increased calcification of coronary arteries, potentially leading to heart attack, and a slightly higher risk of venous thrombosis.This latest discovery expands the scope of these genetic associations, highlighting the potential for blood type to serve as a biomarker for stroke risk.
The findings raise critically important questions about future stroke prevention and treatment strategies. While the study does not suggest individuals with blood type A should promptly alter their lifestyle, it underscores the importance of understanding individual genetic predispositions and tailoring preventative care accordingly. Further research is crucial to determine how these results can be integrated into clinical practice to improve stroke outcomes.
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