Hometown – Mahidol University builds antibody drug to treat dengue fever reduce severe symptoms

Mahidol University continues to produce antibody drugsTreatment of dengue fever reduce severe symptoms

Each year, half the world’s population is at risk of the virus.Dengue fever spread by Aedes mosquitoes, 100 million people need to stay for recovery.in the hospital, but until now There is still no specific drug to treatcure this disease

It has been more than a decade Mahidol University by Center of Research Excellenceantibody, Faculty of Tropical MedicineMate did research to invent antibody drugs.prevent dengue virus which has been tested in rats and monkeys The first generation of antibodies is available from the company.Foreign doctors come to sign investment contracts.commercially developed Now the company has the size of the drug.Will be used to test volunteers in the year.Page (2024), which is an antibody that binds the protein.on the surface of the virus, preventing the virus from entering human cellsYes, with the goal of treating duringPatients have high fever during the first 7 days of infection, but the problem is the severity of the disease, such as low platelets leakage of blood vessels and increasedViruses occur 7 days after the first generation of drugs cannot be detected.The current business has been extended.develop new antibodiesin reducing the severity of the disease over the next 7 days.

Special Professor Dr. Pongram Ramasuta, Head of the Center of Excellence inAntibody Research Institute Department of Social and Environmental MedicineEnvironment, Faculty of Tropical Medicine Mahidol University Revealing the latest achievements at Associate Professor Dr. Pannamthip Ramasuta, PhD student Ms. Ronjanawan Suthichot and the research team were able to develop a new type of antibody drug.increased efficiencyin reducing the severity of leprosy.out with a patent and published in the journal“Biomedicines 2023, 11(1), 227” this year.

This new generation of antibodies can inhibit the virus during the first 7 days and can also reduce the severityThe severity of the disease will occur in the 7 days after infection as well. which will be the first timeTreatment of dengue fever that treats symptomsdisease in both stages

In addition, this innovative antibodyhas been selected forled the project to develop into a commercial “Lab to Market” from “Yothee Medical Innovation District” (Yothee Medical Innovation District – YMID), which is under National Innovation Agency (National Innovation Agency)Public Company Limited). At this time, a Spin off company has been established to develop this innovation to the public.commercial

The results of such research arelaboratory experiments There is a real test scheduled in Volunteers.in the year 2024, which will be an investment inPicture of a worthy country with the potential of being an antidoteperfect body which can be used to treat leprosyEfficiently abstainfuture picture

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